Journal ArticleDOI
Salivary cortisol as a biomarker in stress research.
TLDR
The present paper addresses several psychological and biological variables, which may account for such dissociations, and aims to help researchers to rate the validity and psychobiological significance of salivary cortisol as an HPAA biomarker of stress in their experiments.About:
This article is published in Psychoneuroendocrinology.The article was published on 2009-02-01. It has received 1472 citations till now. The article focuses on the topics: Adrenocorticotropic hormone.read more
Citations
More filters
Journal ArticleDOI
Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge.
TL;DR: This overview demonstrates the role of age and gender, endogenous and exogenous sex steroid levels, pregnancy, lactation and breast-feeding, smoking, coffee and alcohol consumption as well as dietary energy supply in salivary cortisol responses to acute stress.
Journal ArticleDOI
Measuring stress in wildlife: techniques for quantifying glucocorticoids
Michael J. Sheriff,Michael J. Sheriff,Ben Dantzer,Brendan Delehanty,Rupert Palme,Rudy Boonstra +5 more
TL;DR: An overview of the four main biological samples that have been utilized, their advantages and disadvantages for use with wildlife, and some of the background and pitfalls that users must consider in interpreting their results are given.
Journal ArticleDOI
Assessment of the cortisol awakening response: Expert consensus guidelines.
Tobias Stalder,Clemens Kirschbaum,Brigitte M. Kudielka,Emma K. Adam,Jens C. Pruessner,Stefan Wüst,Samantha Dockray,Nina Smyth,Phil Evans,Dirk H. Hellhammer,Robert Miller,Mark Wetherell,Sonia J. Lupien,Angela Clow +13 more
TL;DR: Consensus guidelines are presented on central aspects of CAR assessment, including objective control of sampling accuracy/adherence, participant instructions, covariate accounting, sampling protocols, quantification strategies as well as reporting and interpreting of CAR data.
Journal ArticleDOI
The influence of urban green environments on stress relief measures: A field experiment
TL;DR: In this paper, the authors investigated the psychological and physiological effects of short-term visits to urban nature environments, and found that the salivary cortisol level decreased in a similar fashion in all three urban environments during the experiment.
Journal ArticleDOI
The cortisol awakening response: more than a measure of HPA axis function.
TL;DR: Evidence is presented for reduced adrenal sensitivity to rising levels of ACTH in the pre-awakening period, mediated by an extra-pituitary pathway to the adrenal from the suprachiasmatic nucleus (SCN).
References
More filters
Journal ArticleDOI
Dissociation of ACTH and glucocorticoids.
TL;DR: The separation of adrenocorticotropic hormone and corticosteroid secretion is of clinical relevance and should be incorporated into the view on endocrine stress regulation.
Journal ArticleDOI
Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index
Elisabeth F.C. van Rossum,Jan W. Koper,Annewieke W. van den Beld,André G. Uitterlinden,Pascal P. Arp,Wietske A. Ester,Joop A. M. J. L. Janssen,Albert O. Brinkmann,Frank H. de Jong,Diederick E. Grobbee,Huibert A. P. Pols,Steven W. J. Lamberts +11 more
TL;DR: The sequence alteration of a previously described intronic BclI polymorphism of the GR gene was studied, and it was investigated whether there was an association with sensitivity to glucocorticoids and anthropometric parameters in a group of healthy elderly individuals.
Journal ArticleDOI
Neuroimmunoendocrine circuitry of the 'brain-skin connection'.
TL;DR: The skin and its appendages enable the study of complex neuroimmunoendocrine responses that peripheral tissues launch upon stress exposure, as a basis for identifying new targets for therapeutic stress intervention.
Journal ArticleDOI
Use of saliva for monitoring unbound free cortisol levels in serum
TL;DR: Saliva cortisol can be used sufficiently to monitor its unbound free concentrations in serum, and a well-defined diurnal rhythm and greater response to ACTH stimulation were observed in saliva cortisol than in serum total cortisol.
Journal Article
A human glucocorticoid receptor gene variant that increases the stability of the glucocorticoid receptor beta-isoform mRNA is associated with rheumatoid arthritis.
Roel H. DeRijk,Marcel J. M. Schaaf,G Turner,Nicole A. Datson,Erno Vreugdenhil,John A. Cidlowski,E.R. de Kloet,P Emery,Esther M. Sternberg,S D Detera-Wadleigh +9 more
TL;DR: The findings show an association between RA and a previously unreported polymorphism in the hGR gene that increased stability of hGRbeta mRNA, which could contribute to an altered glucocorticoid sensitivity since the h GRbeta is thought to function as an inhibitor of h GRalpha activity.