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Journal ArticleDOI

Salivary cortisol as a biomarker in stress research.

TLDR
The present paper addresses several psychological and biological variables, which may account for such dissociations, and aims to help researchers to rate the validity and psychobiological significance of salivary cortisol as an HPAA biomarker of stress in their experiments.
About
This article is published in Psychoneuroendocrinology.The article was published on 2009-02-01. It has received 1472 citations till now. The article focuses on the topics: Adrenocorticotropic hormone.

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Stress, the HPA axis, and nonhuman primate well-being: A review

TL;DR: Findings parallel human clinical studies demonstrating that neuropsychiatric disorders may be associated with either increased or decreased activity of the HPA system, depending on the aetiology and manifestation of the disorder and their potential influence in provoking allostatic shifts in system functioning.
Journal ArticleDOI

An LTCC-based microfluidic system for label-free, electrochemical detection of cortisol

TL;DR: In this paper, a fully automated low temperature co-fired ceramic (LTCC) based microfluidic system with an integrated electrochemical biosensing platform for the detection of cortisol was presented.
Journal ArticleDOI

Salivary Alpha-Amylase as a Biomarker of Stress in Behavioral Medicine.

TL;DR: Evidence is presented that sAA can serve as a feasible biomarker of ANS (dys)function in health and disease, and important methodological considerations for readers to keep in mind when including sAA assessments in their own studies are highlighted.
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High indoor CO2 concentrations in an office environment increases the transcutaneous CO2 level and sleepiness during cognitive work

TL;DR: It is shown that a high concentration of CO2 in indoor air seem to be one parameter causing physiological effects, which can decrease the facility user's functional ability, and the correct amount of ventilation with relation to the number of people using the facility, functional air distribution, and regular breaks can counteract the decrease in functional ability.
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Polarity- and valence-dependent effects of prefrontal transcranial direct current stimulation on heart rate variability and salivary cortisol

TL;DR: The findings suggest that tDCS induced transient, polarity specific modulatory top-down effects with anodal tDCS leading to a down-regulation of HPA and SAM systems, and further research should explore the mechanisms of stress regulation in healthy and clinical samples.
References
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Journal ArticleDOI

Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary-adrenal axis.

TL;DR: Although men seem to have a stronger hypothalamic drive in response to stressful stimulation than women, differences in salivary-free cortisol levels, at least in part, may be explained by estradiol-induced changes in corticosteroid-binding protein levels.
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Free Cortisol Levels after Awakening: A Reliable Biological Marker for the Assessment of Adrenocortical Activity

TL;DR: Early morning cortisol levels can be a reliable biological marker for the individual's adrenocortical activity when measured repeatedly with strict reference to the time of awakening, in contrast to single assessments at fixed times.
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Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat

TL;DR: It is suggested that maternal care during infancy serves to "program" behavioral responses to stress in the offspring by altering the development of the neural systems that mediate fearfulness.
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Limbic system mechanisms of stress regulation: hypothalamo-pituitary-adrenocortical axis.

TL;DR: The influence of the limbic system on the HPA axis is likely the end result of the overall patterning of responses to given stimuli and glucocorticoids, with the magnitude of the secretory response determined with respect to the relative contributions of the various structures.
Journal ArticleDOI

The cortisol awakening response (CAR): Facts and future directions

TL;DR: It is hypothesized that the anticipation of the upcoming day is of major relevance for the magnitude of the cortisol awakening response, and considerations are addressed concerning the exact function of the CAR.
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