Journal ArticleDOI
Salivary cortisol as a biomarker in stress research.
TLDR
The present paper addresses several psychological and biological variables, which may account for such dissociations, and aims to help researchers to rate the validity and psychobiological significance of salivary cortisol as an HPAA biomarker of stress in their experiments.About:
This article is published in Psychoneuroendocrinology.The article was published on 2009-02-01. It has received 1472 citations till now. The article focuses on the topics: Adrenocorticotropic hormone.read more
Citations
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Why do we respond so differently? Reviewing determinants of human salivary cortisol responses to challenge.
TL;DR: This overview demonstrates the role of age and gender, endogenous and exogenous sex steroid levels, pregnancy, lactation and breast-feeding, smoking, coffee and alcohol consumption as well as dietary energy supply in salivary cortisol responses to acute stress.
Journal ArticleDOI
Measuring stress in wildlife: techniques for quantifying glucocorticoids
Michael J. Sheriff,Michael J. Sheriff,Ben Dantzer,Brendan Delehanty,Rupert Palme,Rudy Boonstra +5 more
TL;DR: An overview of the four main biological samples that have been utilized, their advantages and disadvantages for use with wildlife, and some of the background and pitfalls that users must consider in interpreting their results are given.
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Assessment of the cortisol awakening response: Expert consensus guidelines.
Tobias Stalder,Clemens Kirschbaum,Brigitte M. Kudielka,Emma K. Adam,Jens C. Pruessner,Stefan Wüst,Samantha Dockray,Nina Smyth,Phil Evans,Dirk H. Hellhammer,Robert Miller,Mark Wetherell,Sonia J. Lupien,Angela Clow +13 more
TL;DR: Consensus guidelines are presented on central aspects of CAR assessment, including objective control of sampling accuracy/adherence, participant instructions, covariate accounting, sampling protocols, quantification strategies as well as reporting and interpreting of CAR data.
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The influence of urban green environments on stress relief measures: A field experiment
TL;DR: In this paper, the authors investigated the psychological and physiological effects of short-term visits to urban nature environments, and found that the salivary cortisol level decreased in a similar fashion in all three urban environments during the experiment.
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The cortisol awakening response: more than a measure of HPA axis function.
TL;DR: Evidence is presented for reduced adrenal sensitivity to rising levels of ACTH in the pre-awakening period, mediated by an extra-pituitary pathway to the adrenal from the suprachiasmatic nucleus (SCN).
References
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Journal ArticleDOI
Clomipramine In Vitro Reduces Glucocorticoid Receptor Function in Healthy Subjects but not in Patients with Major Depression
Livia A. Carvalho,Mario Francisco Juruena,Mario Francisco Juruena,Andrew Papadopoulos,Andrew Papadopoulos,Lucia Poon,Lucia Poon,Robert Kerwin,Anthony J. Cleare,Anthony J. Cleare,Carmine M. Pariante +10 more
TL;DR: The results show that glucocorticoids (dexamethasone, prednisolone, cortisol and corticosterone) caused a concentration-dependent inhibition of LPS-stimulated IL-6 levels, and depressed patients, who were clinically treatment resistant, showed a lack of effect of the antidepressant in vitro.
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Familial/sporadic glucocorticoid resistance: clinical phenotype and molecular mechanisms.
TL;DR: This review focuses on the mechanisms of GR action and the clinical manifestations and molecular mechanisms of familial/sporadic glucocorticoid resistance, which has been ascribed to mutations in the GR gene.
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Glucocorticoid Measurements in Health and Disease - Metabolic Implications and the Potential of 24-h Urine Analyses
TL;DR: The currently used measurements for blood, saliva, and urine samples and the corresponding physiological and metabolic implications are critically reviewed and a special emphasis is placed on the potential of 24-h urine analyses to assess not only glucocorticoid secretion, but also functional glucocortex activity.
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Characterization of the BclI Polymorphism in the Glucocorticoid Receptor Gene
Isabelle Fleury,Patrick Beaulieu,Melanie Primeau,Damian Labuda,Daniel Sinnett,Maja Krajinovic +5 more
TL;DR: Identification of different GR gene variants may be helpful in assessing the role of the GR gene in disease susceptibility or in adjudging predisposition to corticosteroid-associated adverse drug reactions.
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Salivary, total plasma and plasma free cortisol in panic disorder.
TL;DR: All three basal cortisol fractions were significantly elevated in patients compared to controls, and there were significant correlations between all three cortisol fractions.