Journal ArticleDOI
Sarcopenia as a predictor of prognosis in patients following hepatectomy for hepatocellular carcinoma
Norifumi Harimoto,Ken Shirabe,Y. Yamashita,Toru Ikegami,Tomoharu Yoshizumi,Yuji Soejima,Tetsuo Ikeda,Yoshihiko Maehara,Akihiro Nishie,Takahiro Yamanaka +9 more
TLDR
This study investigated the effect of sarcopenia on short‐ and long‐term outcomes following partial hepatectomy for hepatocellular carcinoma (HCC), and aimed to identify prognostic factors.Abstract:
Background: Sarcopenia was identified recently as a poor prognostic factor in patients with cancer. The present study investigated the effect of sarcopenia on short- and long-term outcomes following partial hepatectomy for hepatocellular carcinoma (HCC), and aimed to identify prognostic factors. Methods: Data were collected retrospectively for all consecutive patients who underwent hepatectomy for HCC with curative intent between January 2004 and December 2009. Patients were assigned to one of two groups according to the presence or absence of sarcopenia, assessed by computed tomographic measurement of muscle mass at the level of the third lumbar vertebra. Clinicopathological, surgical outcome and long-term survival data were analysed. Results: Sarcopenia was present in 75 (40·3 per cent) of 186 patients, and was significantly correlated with female sex, lower body mass index and liver dysfunction, as indicated by abnormal serum albumin levels and indocyanine green retention test at 15min values. In patients with, and without sarcopenia, the 5-year overall survival rate was 71 and 83·7 per cent respectively, and the 5-year recurrence-free survival rate was 13 and 33·2 per cent respectively. Multivariable analysis revealed that reduced skeletal muscle mass was predictive of an unfavourable prognosis. Conclusion: Sarcopenia was predictive of worse overall survival even when adjusted for other known predictors in patients with HCC after partial hepatectomy.read more
Citations
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Detección y evaluación del papel de la sarcopenia en ancianos con cáncer tratados con quimioterapia. Proyecto ONCOSARCO
María José Molina Garrido,Carmen Guillén Ponce,Borja Manuel Fernández Félix,Maria del Mar Muñoz Sánchez,Maria del Carmen Soriano Rodríguez,Amaya Olaverri Hernández,Jose Antonio Santiago Crespo +6 more
TL;DR: Se espera that del analisis definitivo of this proyecto puedan encontrarse factores predictores of toxicidad a quimioterapia en ancianos oncologicos.
Journal ArticleDOI
Influence of Internal Iliac Artery Embolization during Endovascular Aortic Repair Regarding Postoperative Sarcopenia and Midterm Survival
Shun Kurose,Yutaka Matsubara,Yutaka Matsubara,Shinichiro Yoshino,Ken Nakayama,Sho Yamashita,Koichi Morisaki,Tadashi Furuyama,Masaki Mori +8 more
TL;DR: IAE during EVAR is a risk factor for postoperative sarcopenia, which is in turn associated with mortality, and it is necessary to preserve the internal iliac artery whenever possible.
Journal ArticleDOI
A New Preoperative Risk Score for Predicting Postoperative Complications in Elderly Patients Undergoing Hepatectomy
Koichi Tomita,Itsuki Koganezawa,Masashi Nakagawa,Shigeto Ochiai,Takahiro Gunji,Kei Yokozuka,Yosuke Ozawa,Kosuke Hikita,Toshimichi Kobayashi,Toru Sano,Naokazu Chiba,Shigeyuki Kawachi +11 more
TL;DR: In this paper, a preoperative evaluation method was developed to predict postoperative complications in patients above 65 years of age using biological impedance analysis (BIA) using clinical data of 59 consecutive patients (aged 65 years or older) who underwent hepatectomy at an institution between 2017 and 2020.
Journal ArticleDOI
Adipose Tissue Distribution Predicts Prognosis of Cirrhotic Patients Undergoing Hepatectomy for Hepatocellular Carcinoma.
Satoshi Okubo,Junichi Shindoh,Yuta Kobayashi,Ryosuke Umino,Miho Akabane,Kazutaka Kojima,Masaji Hashimoto +6 more
TL;DR: In this paper, the authors investigated the prognostic impact of adipose tissue distribution among patients with hepatocellular carcinoma (HCC) undergoing hepatectomy for HCC.
Sarcopenia y algunas de sus características más importantes
TL;DR: Sarcopenia is the perdida de masa and potencia muscular, a lo que se suma el pobre desempeno fisico..
References
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