Journal ArticleDOI
Scleroderma renal crisis
TLDR
More than 60 years after its initial description, SRC still remains an important cause of morbidity and mortality in scleroderma and the prognosis of SRC has improved substantially.About:
This article is published in Seminars in Arthritis and Rheumatism.The article was published on 2015-06-01. It has received 92 citations till now. The article focuses on the topics: Scleroderma Renal Crisis & Scleroderma.read more
Citations
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Journal ArticleDOI
Thrombotic Microangiopathy Care Pathway: A Consensus Statement for the Mayo Clinic Complement Alternative Pathway-Thrombotic Microangiopathy (CAP-TMA) Disease-Oriented Group
Ronald S. Go,Jeffrey L. Winters,Nelson Leung,David L. Murray,Maria Alice V. Willrich,Roshini S. Abraham,Hatem Amer,William J. Hogan,Ariela L. Marshall,Sanjeev Sethi,Cheryl L. Tran,Dong Chen,Rajiv K. Pruthi,Aneel A. Ashrani,Fernando C. Fervenza,Carl H. Cramer,Vilmarie Rodriguez,Alexandra P. Wolanskyj,Stephan D. Thomé,C. Christopher Hook,Vesna D. Garovic,Jennifer C. Yui,Juliana Perez Botero +22 more
TL;DR: This statement represents the joint recommendations from a multidisciplinary team of Mayo Clinic physicians specializing in the management of TMA, a series of evidence- and consensus-based clinical pathways developed to allow a uniform approach to the spectrum of care.
Journal ArticleDOI
Systemic lupus erythematosus and systemic sclerosis: All roads lead to platelets.
Marc Scherlinger,Vivien Guillotin,Marie-Elise Truchetet,Cécile Contin-Bordes,Vanja Sisirak,Pierre Duffau,Estibaliz Lazaro,Christophe Richez,Patrick Blanco +8 more
TL;DR: The main pathogenic implications of platelet activation in both systemic sclerosis and systemic lupus erythematosus are understood and potential therapeutics targeting platelets are discussed.
Journal ArticleDOI
Endothelial Dysfunction and Nailfold Videocapillaroscopy Pattern as Predictors of Digital Ulcers in Systemic Sclerosis: a Cohort Study and Review of the Literature.
Ivone Vieira da Silva,Andreia Teixeira,José Carlos Oliveira,Isabel Almeida,Rui Almeida,Artur P. Águas,Carlos Vasconcelos +6 more
TL;DR: Late scleroderma patterns in NVC are the best independent predictors of SSc patients who are at risk of developing Raynaud's phenomenon and digital ulcers and endothelial dysfunction assessed by FMD and ET-1 was found to be an independent predictor of DU recurrence in a 3-year follow-up.
Journal ArticleDOI
Diagnostic criteria, severity classification and guidelines of systemic sclerosis.
Yoshihide Asano,Masatoshi Jinnin,Yasushi Kawaguchi,Masataka Kuwana,Daisuke Goto,Shinichi Sato,Kazuhiko Takehara,Masaru Hatano,Manabu Fujimoto,Naoki Mugii,Hironobu Ihn +10 more
TL;DR: The clinical guideline was established by clinical questions based on evidence‐based medicine according to the New Minds Clinical Practice Guideline Creation Manual and aimed to make the guideline easy to use and reliable based on the newest evidence.
Journal ArticleDOI
The Frequency of Scleroderma Renal Crisis over Time: A Metaanalysis
Matthew A. Turk,Janet E. Pope +1 more
TL;DR: It appears that SRC remains uncommon in lcSSc and the rate in the dcSSc group may be stable over time, and increasing awareness of SRC could lead to higher rates in more recent years and/or better survival from SRC, but this was not observed.
References
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Journal ArticleDOI
Changes in causes of death in systemic sclerosis, 1972-2002.
TL;DR: The change in the pattern of scleroderma-related deaths over the past 30 years demonstrates that the lung (both pulmonary hypertension and PF) is the primary cause of sclerosis- related deaths today.
Journal ArticleDOI
Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials And Research group database
Ulrich A. Walker,A Tyndall,L. Czirják,Christopher P. Denton,Dominique Farge-Bancel,Otylia Kowal-Bielecka,Ulf Müller-Ladner,Chiara Bocelli-Tyndall,Marco Matucci-Cerinic +8 more
TL;DR: The clinical distinction seemed to be superseded by an antibody-based classification in predicting some scleroderma complications, and the EUSTAR MEDS database facilitates the analysis of clinical patterns in SSc, and contributes to the standardised assessment and monitoring of SSc internationally.
Journal ArticleDOI
Autoantibodies in systemic sclerosis.
TL;DR: In this article, the authors describe the clinical, laboratory, and prognostic features associated with the scleroderma-specific autoantibodies, including demographic, clinical features, organ system outcomes, and survival within the patients with a specific antibody.
Journal ArticleDOI
Case-control study of corticosteroids and other drugs that either precipitate or protect from the development of scleroderma renal crisis
TL;DR: This retrospective case-control study has shown a significant association between antecedent high-dose corticosteroid therapy and the development of scleroderma renal crisis (SRC), and should discourage the use of high-drugs in patients with early diffuse SRC who are at increased risk of developing SRC.
Journal ArticleDOI
Outcome of renal crisis in systemic sclerosis: relation to availability of angiotensin converting enzyme (ACE) inhibitors.
TL;DR: Improved survival and successful discontinuation of dialysis are possible when ACE inhibitors are used to treat scleroderma renal crisis and patients with systemic sclerosis who develop hypertension should be treated with an ACE inhibitor.
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