Searching for a consensus five-factor model of the Positive and Negative Syndrome Scale for schizophrenia.
R.S. Wallwork,Rebecca G. Fortgang,Ryota Hashimoto,Daniel R. Weinberger,Daniel R. Weinberger,Dwight Dickinson +5 more
TLDR
Although the developers of the Positive and Negative Syndrome Scale (PANSS) grouped items into three subscales, factor analyses indicate that a five-factor model better characterizes PANSS data, but lack of consensus on which model to use limits the comparability of PANSS variables across studies.About:
This article is published in Schizophrenia Research.The article was published on 2012-05-01 and is currently open access. It has received 643 citations till now. The article focuses on the topics: Positive and Negative Syndrome Scale.read more
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Comprehensive Versus Usual Community Care for First-Episode Psychosis: 2-Year Outcomes From the NIMH RAISE Early Treatment Program
John M. Kane,Delbert G. Robinson,Nina R. Schooler,Kim T. Mueser,David L. Penn,Robert A. Rosenheck,Jean Addington,Mary F. Brunette,Christoph U. Correll,Sue E. Estroff,Patricia Marcy,James Robinson,Piper Meyer-Kalos,Jennifer D. Gottlieb,Shirley M. Glynn,David W. Lynde,Ronny Pipes,Benji T. Kurian,Alexander L. Miller,Susan T. Azrin,Amy B. Goldstein,Joanne B. Severe,Haiqun Lin,Kyaw Sint,Majnu John,Robert K. Heinssen +25 more
TL;DR: Comprehensive care for first-episode psychosis can be implemented in U.S. community clinics and improves functional and clinical outcomes, and effects are more pronounced for those with shorter duration of untreated psychosis.
Journal ArticleDOI
The influence of illness-related variables, personal resources and context-related factors on real-life functioning of people with schizophrenia
Silvana Galderisi,Alessandro Rossi,Paola Rocca,Alessandro Bertolino,Armida Mucci,Paola Bucci,Paola Rucci,Dino Gibertoni,Eugenio Aguglia,Mario Amore,Antonello Bellomo,Massimo Biondi,Roberto Brugnoli,Liliana Dell'Osso,Diana De Ronchi,Gabriella Di Emidio,Massimo Di Giannantonio,Andrea Fagiolini,Carlo Marchesi,Palmiero Monteleone,Lucio Oldani,Federica Pinna,Rita Roncone,Emilio Sacchetti,Paolo Santonastaso,Alberto Siracusano,Antonio Vita,Patrizia Zeppegno,Mario Maj +28 more
TL;DR: The observed complex associations among investigated predictors, mediators and real‐life functioning strongly suggest that integrated and personalized programs should be provided as standard treatment to people with schizophrenia.
Journal ArticleDOI
Negative symptoms of schizophrenia: new developments and unanswered research questions
TL;DR: If substantial progress is to be made in the understanding and treatment of negative symptoms, then advances in concepts and assessment should be integrated into the design of future studies of these symptoms.
Journal ArticleDOI
Negative symptoms of schizophrenia: clinical features, relevance to real world functioning and specificity versus other CNS disorders.
George Foussias,George Foussias,Ofer Agid,Gagan Fervaha,Gagan Fervaha,Gary Remington,Gary Remington +6 more
TL;DR: The transdiagnostic presence and relevance of negative symptoms highlights the need for continued exploration of their phenomenology and neurobiology as they move to develop effective interventions to address these debilitating symptoms and improve functional outcomes.
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Cytokines and C-reactive protein alterations with respect to cognitive impairment in schizophrenia and bipolar disorder: A systematic review.
Błażej Misiak,Bartłomiej Stańczykiewicz,Kamila Kotowicz,Janusz K. Rybakowski,Jerzy Samochowiec,Dorota Frydecka +5 more
TL;DR: A systematic review of studies investigating the association between peripheral levels of cytokines and C-reactive protein (CRP), cytokine gene polymorphisms and cognition in patients with schizophrenia and bipolar disorder suggests peripheral inflammation might be related to cognitive deficits in schizophrenia and BD.
References
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Book
Principles and Practice of Structural Equation Modeling
TL;DR: The book aims to provide the skills necessary to begin to use SEM in research and to interpret and critique the use of method by others.
Journal ArticleDOI
The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia
TL;DR: Review of five studies involving the PANSS provided evidence of its criterion-related validity with antecedent, genealogical, and concurrent measures, its predictive validity, its drug sensitivity, and its utility for both typological and dimensional assessment.
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An empirical evaluation of alternative methods of estimation for confirmatory factor analysis with ordinal data.
David B. Flora,Patrick J. Curran +1 more
TL;DR: Estimation of polychoric correlations is robust to modest violations of underlying normality and WLS performed adequately only at the largest sample size but led to substantial estimation difficulties with smaller samples.
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The Effects of Risperidone on the Five Dimensions of Schizophrenia Derived by Factor Analysis: Combined Results of the North American Trials
TL;DR: The large between-group differences on negative symptoms, hostility/excitement, and anxiety/depression suggest that risperidone and other serotonin/dopamine antagonists have qualitatively different effects from those of conventional antipsychotic agents.
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DSM-IV-TR: Diagnostic and Statistical Manual of Mental Disorders
TL;DR: The Diagnostic and Statistical Manual of Mental Disorders (DSM), published by the APA, is used for clinical, research, and educational purposes and the focus is on diagnostic codes for psychological disorders and on medical record keeping.
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Keith H. Nuechterlein,Michael F. Green,Robert S. Kern,Lyle E. Baade,M Deanna,Jonathan D. Cohen,Susan M. Essock,Wayne S. Fenton,Frederick J. Frese,James M. Gold,Terry E. Goldberg,Robert K. Heaton,Richard S.E. Keefe,Helena C. Kraemer,Raquelle I. Mesholam-Gately,Larry J. Seidman,Ellen Stover,Daniel R. Weinberger,Alexander S. Young,Steven Zalcman,Stephen R. Marder +20 more