Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women
TLDR
The effects of soy protein (40 g/d) containing moderate and higher concentrations of isoflavones on blood lipid profiles, mononuclear cell LDL receptor messenger RNA, and bone mineral density and content were investigated in 66 free- living, hypercholesterolemic, postmenopausal women during a 6-mo, parallel-group, double-blind trial with three interventions as discussed by the authors.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 1998-12-01 and is currently open access. It has received 862 citations till now. The article focuses on the topics: Soy protein & Blood lipids.read more
Citations
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Bioavailability and bioefficacy of polyphenols in humans. II. Review of 93 intervention studies
Gary Williamson,Claudine Manach +1 more
TL;DR: It is time to rethink the design of in vitro and in vivo studies, so that these issues are carefully considered, and the length of human intervention studies should be increased, to more closely reflect the long-term dietary consumption of polyphenols.
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Legumes and soybeans: overview of their nutritional profiles and health effects
TL;DR: Nutritionists should make a concerted effort to encourage the public to consume more beans in general and more soyfoods in particular to reduce the risk of osteoporosis.
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The Clinical Importance of the Metabolite Equol—A Clue to the Effectiveness of Soy and Its Isoflavones
TL;DR: It is now apparent that there are two distinct subpopulations of people and that "bacterio-typing" individuals for their ability to make equol may hold the clue to the effectiveness of soy protein diets in the treatment or prevention of hormone-dependent conditions.
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Dietary Isoflavones: Biological Effects and Relevance to Human Health
TL;DR: This review focuses on the more recent studies pertinent to this field and includes, where appropriate, the landmark and historical literature that has led to the exponential increase in interest in phytoestrogens from a clinical nutrition perspective.
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Nutritional and Health Benefits of Soy Proteins
Mendel Friedman,David L. Brandon +1 more
TL;DR: The composition in relation to properties of soy proteins is discussed, which include soy-induced lowering of cholesterol, anticarcinogenic effects of BBI, and protective effects against obesity, diabetes, irritants of the digestive tract, bone, and kidney diseases, whereas the latter include poor digestibility and allergy to soy proteins.
References
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Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
TL;DR: A new method of total RNA isolation by a single extraction with an acid guanidinium thiocyanate-phenol-chloroform mixture is described, providing a pure preparation of undegraded RNA in high yield and can be completed within 4 h.
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Meta-Analysis of the Effects of Soy Protein Intake on Serum Lipids
TL;DR: It is found that the consumption of soy protein rather than animal protein significantly decreased serum concentrations of total cholesterol, LDL cholesterol, and triglycerides without significantly affecting serum HDL cholesterol concentrations.
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Quantitation of mRNA by the Polymerase Chain Reaction
TL;DR: This quantitative PCR method provides a rapid and reliable way to quantify the amount of a specific mRNA in a sample of less than 0.1 ng of total RNA.
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Estrogen replacement therapy and coronary heart disease: A quantitative assessment of the epidemiologic evidence☆☆☆
TL;DR: The bulk of the evidence strongly supports a protective effect of estrogens that is unlikely to be explained by confounding factors and is consistent with the effect of Estrogen on lipoprotein subfractions.
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Separation and quantitation of subclasses of human plasma high density lipoproteins by a simple precipitation procedure.
TL;DR: A simple precipitation method for the separation of HDL subclasses in human plasma found that HDL2 is the more variable component and may be a more meaningful index of altered HDL metabolism.