Open AccessJournal Article
Specificity and basis of the tissue polypeptide antigen.
Björklund B,Björklund +1 more
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TLDR
The hypothesis that TPA is related to proliferative activity in general is led to by extensive clinical studies and use of TPA, which could be helpful to use as a monitor of cell proliferation in the further search for local and general causes of proliferation.About:
This article is published in Cancer Detection and Prevention.The article was published on 1983-01-01 and is currently open access. It has received 63 citations till now. The article focuses on the topics: Cell culture & Cancer cell.read more
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Full-length cytokeratin-19 is released by human tumor cells: a potential role in metastatic progression of breast cancer
Catherine Alix-Panabières,Jean-Pierre Vendrell,Monique Slijper,Olivier Pellé,Eric Barbotte,Gregoire Mercier,William Jacot,Michel Fabbro,Klaus Pantel +8 more
TL;DR: Full-length CK19 is released by viable epithelial tumor cells, and CK19-RCs might constitute a biologically active subset of breast cancer cells with high metastatic properties.
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The serum assay of tumour markers in the prognostic evaluation, treatment monitoring and follow-up of patients with cervical cancer: a review of the literature.
TL;DR: Serum levels of vascular endothelial growth factor [VEGF] are often elevated in patients with cervical cancer, and decrease significantly after successful treatment, however, the clinical relevance of serum VEGF assay is still investigational.
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A cytokeratin 8-like protein with plasminogen-binding activity is present on the external surfaces of hepatocytes, HepG2 cells and breast carcinoma cell lines
TL;DR: These studies demonstrate that CK 8 or a CK 8-like protein binds plasminogen and support the hypothesis that CK 7 is associated with the external cell surface where it may express important proteinase receptor function.
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Serum tumour markers in lung cancer: history, biology and clinical applications
TL;DR: There is a body of evidence which proves that at least some of these substances may be useful in the evaluation of the course and prognosis of the disease.
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Cytokeratin Markers Come of Age
TL;DR: CK18 is attracting considerable interest as a response biomarker during clinical trials of anticancer drugs because of properties such as excellent antigen stability and the epithelial specificity of cytokeratins contribute to make this biomarker attractive.