Journal ArticleDOI
The catalog of human cytokeratins: Patterns of expression in normal epithelia, tumors and cultured cells
TLDR
During cell transformation and tumor devel- opment this cell type specificity of intermediate filaments is largely conserved’ and classification of tumors by their specific type of intermediate Filaments has re- cently become very valuable in clinical histodiagnosis.About:
This article is published in Cell.The article was published on 1982-11-01. It has received 5173 citations till now. The article focuses on the topics: Intermediate filament cytoskeleton & Cytokeratin.read more
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Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line.
TL;DR: The characteristics of the HaCaT cell line clearly document that spontaneous transformation of human adult keratinocytes can occur in vitro and is associated with sequential chromosomal alterations, though not obligatorily linked to major defects in differentiation.
Journal ArticleDOI
Multi-Organ, Multi-Lineage Engraftment by a Single Bone Marrow-Derived Stem Cell
Diane S. Krause,Neil D. Theise,Michael I. Collector,Octavian Henegariu,Sonya Hwang,Rebekah Gardner,Sara Neutzel,Saul J. Sharkis +7 more
TL;DR: It is shown that rare cells that home to bone marrow can LTR primary and secondary recipients, and this finding may contribute to clinical treatment of genetic disease or tissue repair.
Journal ArticleDOI
Differentiation-related expression of a major 64K corneal keratin in vivo and in culture suggests limbal location of corneal epithelial stem cells.
TL;DR: Keratin expression data suggest that the acidic 55K and basic 64K keratins represent markers for an advanced stage of corneal epithelial differentiation.
Journal ArticleDOI
Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium.
Kohji Nishida,Masayuki Yamato,Yasutaka Hayashida,K. Watanabe,Kazuaki Yamamoto,Eijiro Adachi,Shigeru Nagai,Akihiko Kikuchi,Naoyuki Maeda,Hitoshi Watanabe,Teruo Okano,Yasuo Tano +11 more
TL;DR: Sutureless transplantation of carrier-free cell sheets composed of autologous oral mucosal epithelial cells may be used to reconstruct corneal surfaces and can restore vision in patients with bilateral severe disorders of the ocular surface.
References
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Journal ArticleDOI
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products.
Journal Article
Cleavage of structural proteins during the assemble of the head of bacterio-phage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products as mentioned in this paper.
Journal ArticleDOI
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.
TL;DR: A method has been devised for the electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets that results in quantitative transfer of ribosomal proteins from gels containing urea.
Journal ArticleDOI
High resolution two-dimensional electrophoresis of proteins.
TL;DR: This technique provides a method for estimation of the number of proteins made by any biological system and can resolve proteins differing in a single charge and consequently can be used in the analysis of in vivo modifications resulting in a change in charge.
Journal ArticleDOI
High resolution two-dimensional electrophoresis of basic as well as acidic proteins
TL;DR: This paper describes an alternate procedure for the first dimension which, unlike isoelectric focusing, resolves basic as well as acidic proteins, and involves a short time of electrophoresis toward the cathode and separates most proteins according to their isoelection points.
Related Papers (5)
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
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Elaine Fuchs,Howard Green +1 more