Journal ArticleDOI
Stereoselective radical azidooxygenation of alkenes.
Bo Zhang,Armido Studer +1 more
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TLDR
Yields are good to excellent, and for cyclic systems azidooxygenation occurs with excellent diastereoselectivity, and the C-radical generated after N3-radical addition is efficiently trapped by in situ generated TEMPO.About:
This article is published in Organic Letters.The article was published on 2013-08-09. It has received 170 citations till now. The article focuses on the topics: Radical cyclization & Reagent.read more
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Advances in Synthetic Applications of Hypervalent Iodine Compounds
TL;DR: One of the goals of this Review is to attract the attention of the scientific community as to the benefits of using hypervalent iodine compounds as an environmentally sustainable alternative to heavy metals.
"Clicking" polymers or just efficient linking: What is the difference?
Christopher Barner-Kowollik,F. Du Prez,Pieter Espeel,Craig J. Hawker,Thomas Junkers,Helmut Schlaad,W. Van Camp +6 more
TL;DR: The original click criteria are evaluated in this Essay specifically for the synthetic polymer field and a set of criteria are specified that distinguishes click from other efficient reactions.
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An Electrocatalytic Approach to the Radical Difunctionalization of Alkenes
Gregory S. Sauer,Song Lin +1 more
TL;DR: In this article, the design principles underpinning the development of electrochemical diazidation, dichlorination, and halotrifluoromethylation of alkenes were described.
Journal ArticleDOI
The Persistent Radical Effect in Organic Synthesis
TL;DR: Although great progress has been achieved over the years in enantioselective radical chemistry, the radical-metal crossover approach offers advantages, in particular considering the non-existing background coupling leading to racemic compounds.
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Cyclization cascades via N-amidyl radicals toward highly functionalized heterocyclic scaffolds.
TL;DR: A silver-catalyzed radical cascade process involving the sequential formation of two new C-C bonds and one C-N bond, a formal 1,4-aryl migration, and desulfonylation of the starting material explains the regioselective formation of densely functionalized heterocycles in a straightforward manner.
References
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Click Chemistry: Diverse Chemical Function from a Few Good Reactions.
TL;DR: In this paper, a set of powerful, highly reliable, and selective reactions for the rapid synthesis of useful new compounds and combinatorial libraries through heteroatom links (C-X-C), an approach called click chemistry is defined, enabled, and constrained by a handful of nearly perfect "springloaded" reactions.
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Chemistry of Polyvalent Iodine
TL;DR: The present review summarizes the data that appeared in the literature following publication of previous reviews in 1996 and 2002 and is organized according to the classes of organic polyvalent iodine compounds with emphasis on their synthetic application.
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The persistent radical effect: a principle for selective radical reactions and living radical polymerizations.
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A "Renaissance" in radical trifluoromethylation
TL;DR: The present article addresses the radical trifluoromethylation of alkenes and arenes mainly focussing on recent achievements, however, important earlier work in this field is also covered.
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Hypervalent iodine chemistry in synthesis: scope and new directions.
TL;DR: This contribution summarizes recent achievements and highlights key findings and developments that will influence future research and lead to novel applications of hypervalent iodine reagents in synthesis.