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Journal ArticleDOI

Stress and protective factors in individuals at ultra-high risk for psychosis, first episode psychosis and healthy controls.

TLDR
Stress was the only significant predictor for both symptom measures and that the relationship was not moderated by self-esteem, and psychosocial interventions targeted at reducing stress levels and improving resilience in this population may be beneficial in improving outcomes.
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This article is published in Schizophrenia Research.The article was published on 2011-06-01. It has received 169 citations till now. The article focuses on the topics: Psychosocial & Psychosis.

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Stress in puberty unmasks latent neuropathological consequences of prenatal immune activation in mice.

TL;DR: Exposure to prenatal immune challenge and peripubertal stress induces synergistic pathological effects on adult behavioral functions and neurochemistry and it is demonstrated that the prenatal insult markedly increases the vulnerability of the pubescent offspring to brain immune changes in response to stress.
Journal ArticleDOI

Social networks, support and early psychosis: a systematic review.

TL;DR: Reduced social networks and support appear to pre-date onset of psychotic disorder, however, the substantial methodological heterogeneity among the existing studies makes comparisons difficult and suggests a need for more robust and comparable studies on networks, support and early psychosis.
Journal ArticleDOI

Disorder, not just state of risk: meta-analysis of functioning and quality of life in people at high risk of psychosis.

TL;DR: The results indicate that the high-risk state is characterised by consistent and large impairments of functioning and reduction in QoL similar to those in other coded psychiatric disorders.
Journal ArticleDOI

The neural diathesis-stress model of schizophrenia revisited: An update on recent findings considering illness stage and neurobiological and methodological complexities.

TL;DR: An extended neural diathesis‐stress model of schizophrenia is proposed that addresses the broader neurobiological context of stress psychobiology in psychosis progression and implications of this model for best practice are discussed.
Journal ArticleDOI

Deconstructing vulnerability for psychosis: Meta-analysis of environmental risk factors for psychosis in subjects at ultra high-risk

TL;DR: The increased vulnerability of UHR subjects can be related to environmental risk factors like childhood trauma, adverse life events and affective dysfunction, and the role of genetic and epigenetic risk factors awaits clarification.
References
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Journal ArticleDOI

The moderator–mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations.

TL;DR: This article seeks to make theorists and researchers aware of the importance of not using the terms moderator and mediator interchangeably by carefully elaborating the many ways in which moderators and mediators differ, and delineates the conceptual and strategic implications of making use of such distinctions with regard to a wide range of phenomena.
Book

Stress, appraisal, and coping

TL;DR: In this paper, the authors present a detailed theory of psychological stress, building on the concepts of cognitive appraisal and coping, which have become major themes of theory and investigation in psychology.
Book

Multiple Regression: Testing and Interpreting Interactions

TL;DR: In this article, the effects of predictor scaling on the coefficients of regression equations are investigated. But, they focus mainly on the effect of predictors scaling on coefficients of regressions.
Journal ArticleDOI

The Multidimensional Scale of Perceived Social Support

TL;DR: The Multidimensional Scale of Perceived Social Support (MSPSS) as discussed by the authors is a self-report measure of subjectively assessed social support, which has good internal and test-retest reliability as well as moderate construct validity.
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What are the key triggers and protective factors for the first depressive episode?

The provided paper does not specifically address the triggers and protective factors for the first depressive episode. The paper focuses on stress and protective factors in individuals at ultra-high risk for psychosis, first episode psychosis, and healthy controls.