Journal ArticleDOI
Structurally diverse α-substituted benzopyran synthesis through a practical metal-free C(sp3)-H functionalization.
TLDR
A metal-free reaction has an excellent functional group tolerance and high chemoselectivity and displays a broad scope with respect to both benzopyran and nucleophile partners, efficiently affording a collection of Benzopyrans bearing diverse skeletons and α-functionalities in one step.About:
This article is published in Organic Letters.The article was published on 2014-11-11. It has received 69 citations till now. The article focuses on the topics: Benzopyrans & Chemoselectivity.read more
Citations
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Journal ArticleDOI
Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations
Journal ArticleDOI
Organocatalysis in Inert C–H Bond Functionalization
Yan Qin,Lihui Zhu,Sanzhong Luo +2 more
TL;DR: This review provides a comprehensive summary of organocatalysis in inert C-H bond functionalization over the past two decades as well as those activated benzylic, allylic, and C- H bonds alpha to the heteroatom such as nitrogen and oxygen.
Journal ArticleDOI
Organocatalytic Enantioselective Oxidative C ? H Alkenylation and Arylation of N‐Carbamoyl Tetrahydropyridines and Tetrahydro‐β‐carbolines
TL;DR: The first organocatalytic enantioselective C-H alkenylation and arylation reactions of N-carbamoyl tetrahydropyridines and tetrahYDro-β-carbolines (THCs) are described.
Journal ArticleDOI
C1-Benzyl and benzoyl isoquinoline synthesis through direct oxidative cross-dehydrogenative coupling with methyl arenes.
Miao Wan,Hong-Xiang Lou,Lei Liu +2 more
TL;DR: An oxidative cross-dehydrogenative coupling of isoquinolines with methyl arenes has been developed, allowing for the facile synthesis of a broad range of structurally diverse C1-benzyl and -benzoyl isoquinoleines.
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Iron Catalyzed Dual-Oxidative Dehydrogenative (DOD) Tandem Annulation of Glycine Derivatives with Tetrahydrofurans
TL;DR: A novel iron-catalyzed dual-oxidative dehydrogenative (DOD) tandem annulation of glycine derivatives with tetrahydrofurans (THFs) for the synthesis of high value quinoline fused lactones has been developed.
References
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Chemical Redox Agents for Organometallic Chemistry
TL;DR: 1. Advantages and disadvantages of Chemical Redox Agents, 2. Reversible vs Irreversible ET Reagents, 3. Categorization of Reagent Strength.
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Cross-dehydrogenative coupling (CDC): exploring C-C bond formations beyond functional group transformations.
TL;DR: This work over the past several years to form carbon-carbon bonds directly from two different C-H bonds under oxidative conditions, cross-dehydrogenative coupling (CDC) is described, which provides an alternative to the separate steps of prefunctionalization and defunctionsalization that have traditionally been part of synthetic design.
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C-H Bond Functionalization in Complex Organic Synthesis
Kamil Godula,Dalibor Sames +1 more
TL;DR: In this paper, the functionalization of C-H bonds in complex organic substrates catalyzed by transition metal catalysts is studied and the key concepts and approaches aimed at achieving selectivity in complex settings are discussed.
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Direct C-H transformation via iron catalysis.
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Bond Formations between Two Nucleophiles: Transition Metal Catalyzed Oxidative Cross-Coupling Reactions
TL;DR: Oxidative X-X Bond Formations between Two Nucleophiles 1819 5.1.