Book ChapterDOI
Structure and Applications of Poly(vinyl alcohol) Hydrogels Produced by Conventional Crosslinking or by Freezing/Thawing Methods
TLDR
In this article, a review of previous work in the development of freezing and thawing processes focusing on the implications of such materials for a variety of applications is presented, and future directions involving the further development of freeze/thawed PVA hydrogels are addressed.Abstract:
Poly(vinyl alcohol) (PVA) is a polymer of great interest because of its many desirable characteristics specifically for various pharmaceutical and biomedical applications. The crystalline nature of PVA has been of specific interest particularly for physically cross-linked hydrogels prepared by repeated cycles of freezing and thawing. This review includes details on the structure and properties of PVA, the synthesis of its hydrogels, the crystallization of PVA, as well as its applications. An analysis of previous work in the development of freezing and thawing processes is presented focusing on the implications of such materials for a variety of applications. PVA blends that have been developed with enhanced properties for specific applications will also be discussed briefly. Finally, the future directions involving the further development of freeze/thawed PVA hydrogels are addressed.read more
Citations
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Journal ArticleDOI
Microfibrillated cellulose and new nanocomposite materials: a review
Istvan Siró,David Plackett +1 more
TL;DR: In this article, a review summarizes progress in nanocellulose preparation with a particular focus on microfibrillated cellulose and also discusses recent developments in bio-nanocomposite fabrication based on nanocells.
Journal ArticleDOI
Hydrogels in regenerative medicine
Brandon V. Slaughter,Shahana S. Khurshid,Omar Z. Fisher,Ali Khademhosseini,Nicholas A. Peppas +4 more
TL;DR: The properties of hydrogels that are important for tissue engineering applications and the inherent material design constraints and challenges are discussed.
Journal ArticleDOI
Hydrogel Nanoparticles in Drug Delivery
TL;DR: Hydrogel nanoparticles have gained considerable attention in recent years as one of the most promising nanoparticulate drug delivery systems owing to their unique potentials via combining the characteristics of a hydrogel system with a nanoparticle, each with its own advantages and drawbacks.
Journal ArticleDOI
A practical guide to hydrogels for cell culture.
TL;DR: Hydrogels are introduced to those who may be unfamiliar with procedures to culture and study cells with these systems, with a particular focus on commercially available hydrogels.
Journal ArticleDOI
A review of polyvinyl alcohol and its uses in cartilage and orthopedic applications.
TL;DR: The purpose of this review is to evaluate the available published information on PVA with respect to its safety as a medical device implant material for cartilage replacement and the safety recommendation involving the further development of PVA cryogels forcartilage replacement is addressed.
References
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Book
Hydrogels in Medicine and Pharmacy
TL;DR: Hydrogels in medicine and pharmacy, Hydrogel-like properties, and their applications in pharmacy and medicine are investigated.
BookDOI
Hydrogels in Medicine and Pharmacy : Fundamentals
TL;DR: In this paper, the authors discuss hydrogels in medicine and pharmacy and their applications in the field of medicine and pharmacology, including the use of hydrogel in medicine.
Journal ArticleDOI
A note on single crystals in polymers: Evidence for a folded chain configuration
TL;DR: In this paper, the morphology and orientation of polyethylene polymers were studied with the electron microscope combined with selected area electron diffraction and it was concluded that the molecules must bend sharply back on themselves forming a regular folded configuration.
Journal ArticleDOI
Poly (vinyl alcohol) hydrogels prepared by freezing-thawing cyclic processing
TL;DR: In this article, a method of preparation of strong polyvinyl alcohol (PVA) hydrogels was developed without utilization of chemical crosslinking or other reinforcing agents, and the results showed that the gel compliance was relatively constant over a wide range of stresses and decreased as the number of freezing-thawing cycles increased.