Open AccessJournal Article
Systematic review on pyrethroid toxicity with special reference to deltamethrin
Hasibur Rehman,Al Thbiani Aziz,Shalini Saggu,Zahid Khorshid Abbas,Anand Mohan,Abid Ali Ansari +5 more
Reads0
Chats0
TLDR
Light is shed on deltamethrin induced various toxicities during acute and chronic exposure in different species.Abstract:
Pyrethroids are synthetic organic compounds synthesized from chrysanthemum flowers that are used extensively as household and commercial insecticides. The keto-alocoholic esters of chrysanthemic and pyrethroic acid being lipophilic are responsible for its insecticidal properties. Pyrethroids are broadly classified into first and second generation pyrethroids. The first generation (Type 1) pyrethroids are less toxic to mammals than the second generation (Type II) pyrethroids. Mainly Type II pyrethroids cause paresthesia, which is characterized by transient burning/tingling/itching sensation of the exposed skin. Also, it has been suggested that some pyrethroids cause developmental neurotoxicity, but available evidence has been judged to be insufficient. While some pyrethroids have been shown to cause tumors in rodent models, the tumor induction does not appear to reflect a common carcinogenic endpoint for this particular subset of compounds. Deltamethrin is an alpha-cyano pyrethroid insecticide used extensively in pest control. Although initially thought to be least toxic, a number of recent reports showed its toxicity in mammalian and non-mammalian laboratory and wildlife animal species. The article sheds light on deltamethrin induced various toxicities during acute and chronic exposure in different species.read more
Citations
More filters
Journal ArticleDOI
Safety of Natural Insecticides: Toxic Effects on Experimental Animals
TL;DR: The review presented here focuses on the safety of natural insecticide products and some natural compounds are toxic and induce adverse effects to experimental animals.
Journal ArticleDOI
Chiral pharmaceuticals: Environment sources, potential human health impacts, remediation technologies and future perspective
Yaoyu Zhou,Shikang Wu,Hao Zhou,Hongli Huang,Jia Zhao,Yaocheng Deng,Hua Wang,Yuan Yang,Jian Yang,Lin Luo +9 more
TL;DR: The current status and sources of chiral pharmaceuticals, potential effects on human health, as well as the superiority, disadvantages and prospects of current advanced remediation technologies are summarized.
Journal ArticleDOI
Sustained release of pesticide (Cypermethrin) from nanocarriers: An effective technique for environmental and crop protection
TL;DR: The study showed that cypermethrin is well encapsulated within calcium alginate nanocarriers without any chemical deformation and could be a promising and safe candidate for sustained and slow release of cypermETHrin and helpful in reducing the environment pollutions caused by excessive use of cy permethrin.
Journal ArticleDOI
Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community.
Stefan-Adrian Strungaru,Gabriel Plavan,Alin Ciobica,Mircea Nicoara,Madalina Andreea Robea,Carmen Solcan,Adriana Petrovici +6 more
TL;DR: The nervous system suffered significant damage for all studied concentrations and confirmed the changes in the behavior, and Selenium concentration in the body decreased and may be involved in the detoxification processes.
Journal Article
Veterinary Toxicology — Basic and Clinical Principles
TL;DR: The second edition of “Veterinary Toxicology — Basic and Clinical Principles” is an excellent reference for veterinarians, students, and veterinary toxicologists, covering the complex topic of veterinary toxicology in a much better format.
References
More filters
Journal ArticleDOI
International programme on chemical safety
TL;DR: The International Programme on Chemical Safety is a joint venture of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization to carry out and disseminate evaluations of the effects of chemicals on human health and the quality of the environment.
Journal Article
Pesticides and oxidative stress: a review.
TL;DR: It is concluded that stimulation of free radical production, induction of lipid peroxidation, and disturbance of the total antioxidant capability of the body are mechanisms of toxicity in most pesticides, including organophosphates, bipyridyl herbicides and organochlorines.
Journal ArticleDOI
Mechanisms of pyrethroid neurotoxicity: Implications for cumulative risk assessment
David M. Soderlund,John M. Clark,Larry P. Sheets,Linda S. Mullin,Vincent J Piccirillo,Dana Sargent,James T Stevens,Myra L. Weiner +7 more
TL;DR: The diverse toxic actions and pharmacological effects of pyrethroids suggest that simple additivity models based on combined actions at a single target are not appropriate to assess the risks of cumulative exposure to multiple pyre Throids.
Journal Article
Reactive oxygen species: oxidative damage and pathogenesis
TL;DR: One of the significant benefits of the studies on ROS will perhaps be in designing of a suitable antioxidant therapy to control the ROS-mediated oxidative damage, and the disease processes.