Journal ArticleDOI
The asymmetric intramolecular Heck reaction in natural product total synthesis.
Amy B. Dounay,Larry E. Overman +1 more
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This article is published in Chemical Reviews.The article was published on 2003-07-08. It has received 1247 citations till now. The article focuses on the topics: Heck reaction & Total synthesis.read more
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Synthesis of 3-amino-3-hydroxymethyloxindoles and 3-hydroxy-3-hydroxymethyloxindoles by Rh2(OAc)4-catalyzed three-component reactions of 3-diazooxindoles with formaldehyde and anilines or water
TL;DR: In this atom- and step-economic transformation, Rh2(OAc)4-catalyzed decomposition of 3-diazooxindoles with anilines or water forms the corresponding active ammonium or oxonium ylides.
Journal ArticleDOI
Direct Observation of Gold/Palladium Transmetalation in an Organogold Heck Reaction
Katrina E. Roth,Suzanne A. Blum +1 more
TL;DR: The results herein furnish experimental evidence for the mechanisms of reactions mediated or catalyzed by both gold and palladium and reveal a migratory insertion strategy for outcompeting homocoupling pathways.
Journal ArticleDOI
Regioselective Heck reaction catalyzed by Pd nanoparticles immobilized on DNA-modified MWCNTs
TL;DR: In this paper, the first report of regioselective Heck reaction of aryl iodides with 2,3-dihydrofuran using heterogonous nanocatalyst was presented.
Journal ArticleDOI
Design of Organic Transformations at Ambient Conditions: Our Sincere Efforts to the Cause of Green Chemistry Practice.
TL;DR: This account summarizes the recent efforts in designing a good number of important organic transformations leading to the synthesis of biologically relevant compounds at room temperature and pressure and highlights the green chemistry practice leading to carbon-carbon and carbon-heteroatom bond-forming reactions of topical significance.
Journal ArticleDOI
Rhodium(I)-catalysed decarbonylative direct C–H vinylation and dienylation of arenes
Jianbin Xu,Changjun Chen,Haoqiang Zhao,Conghui Xu,Yixiao Pan,Xin Xu,Huanrong Li,Lijin Xu,Baomin Fan +8 more
TL;DR: This protocol was efficient under oxidant-free conditions to access synthetically valuable styrenes and 1-aryl-1,3-butadienes in high yields with a broad substrate scope and good functionality tolerance.
References
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BookDOI
Metal-catalyzed cross-coupling reactions
TL;DR: In this paper, the authors present an approach to the formation of C-X (X = N, O, S) bonds in metal-catalyzed cross-coupling reactions.
Journal ArticleDOI
The heck reaction as a sharpening stone of palladium catalysis.
TL;DR: s, or keywords if they used Heck-type chemistry in their syntheses, because it became one of basic tools of organic preparations, a natural way to make organic preparations.
Book
Catalytic Asymmetric Synthesis
TL;DR: Asymmetric Hydrogenation (T. Ohkuma, et al. as discussed by the authors ), asymmetric carbon-Carbon Bond-Forming Reactions (K. Nozaki & I. Negishi). Asymmetric Addition and Insertion Reactions of Catalytically-Generated Metal Carbenes (M. O'Donnell), and asymptotic phase-transfer Reactions.
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Richard F. Heck,J. P. Nolley +1 more