Journal ArticleDOI
The asymmetric intramolecular Heck reaction in natural product total synthesis.
Amy B. Dounay,Larry E. Overman +1 more
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This article is published in Chemical Reviews.The article was published on 2003-07-08. It has received 1247 citations till now. The article focuses on the topics: Heck reaction & Total synthesis.read more
Citations
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Mechanism of nickel-catalyzed direct carbonyl-Heck coupling reaction: the crucial role of second-sphere interactions
TL;DR: In this paper, the authors present a detailed DFT mechanistic study on the first Ni-catalyzed direct carbonyl-Heck coupling of aryl triflates and aldehydes to afford ketones.
Journal ArticleDOI
Enantiomerically pure α-pinene derivatives from material of 65% enantiomeric purity. Part 2: C2-symmetric N,N'-3-(2α-hydroxy)pinane diimines and diamines
Stanislaw Wojciech Markowicz,Marek Figlus,Michał Lejkowski,Janina Karolak-Wojciechowska,Agnieszka Dzierzawska-Majewska,Francis Verpoort +5 more
TL;DR: In this article, the conversion of enantiomerically enriched 2α-hydroxypinan-3-one and its oxime into a range of derivatives with potential application in asymmetric synthesis was attempted.
Journal ArticleDOI
Di-tert-butyl peroxide (DTBP) promoted dehydrogenative coupling: an expedient and metal-free synthesis of oxindoles via intramolecular C(sp2)–H and C(sp3)–H bond activation
Biplab Mondal,Brindaban Roy +1 more
TL;DR: An efficient di-tert-butyl peroxide promoted synthesis of oxindole has been developed and provides an expedient approach to access oxindoles in moderate to very good yields in DCE at 110 °C.
Journal ArticleDOI
Supported Liquid Phase Catalyst coating in micro flow Mizoroki–Heck reaction
TL;DR: In this paper, a Supported Liquid Phase Catalyst (SLPC) coating was successfully applied for the Mizoroki-Heck reaction in micro flow, and the reaction was shown to fit the predictions of the kinetic model.
References
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BookDOI
Metal-catalyzed cross-coupling reactions
TL;DR: In this paper, the authors present an approach to the formation of C-X (X = N, O, S) bonds in metal-catalyzed cross-coupling reactions.
Journal ArticleDOI
The heck reaction as a sharpening stone of palladium catalysis.
TL;DR: s, or keywords if they used Heck-type chemistry in their syntheses, because it became one of basic tools of organic preparations, a natural way to make organic preparations.
Book
Catalytic Asymmetric Synthesis
TL;DR: Asymmetric Hydrogenation (T. Ohkuma, et al. as discussed by the authors ), asymmetric carbon-Carbon Bond-Forming Reactions (K. Nozaki & I. Negishi). Asymmetric Addition and Insertion Reactions of Catalytically-Generated Metal Carbenes (M. O'Donnell), and asymptotic phase-transfer Reactions.
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Richard F. Heck,J. P. Nolley +1 more