The Brain's Reward System in Health and Disease.
TLDR
In this article, the influence of the dopaminergic reward pathways on the circadian system and the implication of this interplay on human health is discussed, and the authors discuss how reward-related activities (e.g., feeding, exercise, sex, substance use, and social interactions) which lead to an elevated level of dopamine, alters rhythms in the suprachiasmatic nucleus and the brain's reward system.Abstract:
Rhythmic gene expression is found throughout the central nervous system. This harmonized regulation can be dependent on- and independent of- the master regulator of biological clocks, the suprachiasmatic nucleus (SCN). Substantial oscillatory activity in the brain's reward system is regulated by dopamine. While light serves as a primary time-giver (zeitgeber) of physiological clocks and synchronizes biological rhythms in 24-h cycles, nonphotic stimuli have a profound influence over circadian biology. Indeed, reward-related activities (e.g., feeding, exercise, sex, substance use, and social interactions), which lead to an elevated level of dopamine, alters rhythms in the SCN and the brain's reward system. In this chapter, we will discuss the influence of the dopaminergic reward pathways on circadian system and the implication of this interplay on human health.read more
Citations
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Impaired interhemispheric synchrony in Parkinson's disease patients with apathy.
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Screen use and sleep duration and quality at 15 years old: Cohort study
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TL;DR: In this paper , the authors investigated the association between screen time for entertainment (watching TV, using computer, or playing games on tablets, smartphones, or videogame consoles) and sleep duration and self-reported sleep quality, among adolescents aged 15 years.
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Deficiency of the circadian clock gene Rev-erbα induces mood disorder-like behaviours and dysregulation of the serotonergic system in mice
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The Effects of Obesity on the Inflammatory, Cardiovascular, and Neurobiological Responses to Exercise in Older Adults
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