Journal ArticleDOI
The essential metals for humans: a brief overview
Maria Antonietta Zoroddu,Jan Aaseth,Guido Crisponi,Serenella Medici,Massimiliano Francesco Peana,Valeria Marina Nurchi +5 more
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TLDR
The human body needs about 20 essential elements in order to function properly and among them, for certain, 10 are metal elements, though for every metal we do need, there is another one in our body we could do without it as discussed by the authors.About:
This article is published in Journal of Inorganic Biochemistry.The article was published on 2019-03-22. It has received 429 citations till now.read more
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The regulation and functions of DNA and RNA G-quadruplexes.
TL;DR: This Review discusses the identification of G4s and evidence for their formation in cells using chemical biology, imaging and genomic technologies, and discusses the connection between G4 formation and synthetic lethality in cancer cells, and recent progress towards considering G 4s as therapeutic targets in human diseases.
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The role of zinc, copper, manganese and iron in neurodegenerative diseases.
TL;DR: Delineating the specific mechanisms by which metals alter redox homeostasis is essential to understand the pathophysiology of AD, PD, and MS and may provide possible new targets for their prevention and treatment of the patients affected by these NDDs.
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Zinc as a Therapeutic Agent in Bone Regeneration
TL;DR: Zinc can positively affect chondrocyte and osteoblast functions, while inhibiting osteoclast activity, consistent with a beneficial role for zinc in bone homeostasis and regeneration.
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Laser additive manufacturing of Mg-based composite with improved degradation behaviour
Youwen Yang,Changfu Lu,Shuping Peng,Shuping Peng,Lida Shen,Di Wang,Fangwei Qi,Cijun Shuai,Cijun Shuai,Cijun Shuai +9 more
TL;DR: In this article, a bioglass-reinforced Mg-based composite was manufactured for bone implant, which showed great potential as bone implant owing to its favorable biocompatibility and degradability.
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Enhancing biocompatibility and corrosion resistance of biodegradable Mg-Zn-Y-Nd alloy by preparing PDA/HA coating for potential application of cardiovascular biomaterials
TL;DR: In vivo implantation of SD rats' celiac artery demonstrated that the PDA/HA-2 had preferable corrosion resistance and biocompatibility, and in vitro biological test suggested better hemocomp compatibility, pro-endothelialization, anti-hyperplasia and anti-inflammation functions of the Pda/ HA-2- and PDA-4-coated Mg-Zn-Y-Nd alloy.
References
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Hard and soft acids and bases
TL;DR: In this paper, the rate data for the generalized nucleophilic displacement reaction were reviewed, and the authors presented a method to estimate the rate of the generalized displacement reaction in terms of the number of nucleophiles.
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The biology of oxygen radicals
TL;DR: The reactive superoxide radical, O2-, formerly of concern only to radiation chemists and radiobiologists, is now understood to be a normal product of the biological reduction of molecular oxygen.
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Diet and Lifestyle Recommendations Revision 2006 A Scientific Statement From the American Heart Association Nutrition Committee
Alice H. Lichtenstein,Lawrence J. Appel,Michael W. Brands,Mercedes R. Carnethon,Stephen R. Daniels,Harold A. Franch,Barry A. Franklin,Penny M. Kris-Etherton,William S. Harris,Barbara V. Howard,Njeri Karanja,Michael Lefevre,Lawrence L. Rudel,Frank M. Sacks,M. Linda Van Horn,Mary Winston,Judith Wylie-Rosett +16 more
TL;DR: Adhering to these diet and lifestyle recommendations, Americans can substantially reduce their risk of developing cardiovascular disease, which remains the leading cause of morbidity and mortality in the United States.
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Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 Å resolution
TL;DR: Comparison with a low-resolution electron density map of the enzyme in the absence of calcium and with biochemical data suggests that large domain movements take place during active transport.
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The Mononuclear Molybdenum Enzymes
TL;DR: It is now well-established that all molybdenum-containing enzymes other than nitrogenase fall into three large and mutually exclusive families, as exemplified by the enzymes xanthine oxidation, sulfite oxidase, and DMSO reductase; these enzymes represent the focus of the present account.