Journal ArticleDOI
The genetical structure of populations
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This article is published in Annals of Human Genetics.The article was published on 1949-01-01. It has received 6139 citations till now. The article focuses on the topics: Population.read more
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Estimating F-statistics for the analysis of population structure.
Bruce S. Weir,C. Clark Cockerham +1 more
TL;DR: The purpose of this discussion is to offer some unity to various estimation formulae and to point out that correlations of genes in structured populations, with which F-statistics are concerned, are expressed very conveniently with a set of parameters treated by Cockerham (1 969, 1973).
Journal ArticleDOI
Arlequin (version 3.0): An integrated software package for population genetics data analysis
TL;DR: Arlequin ver 3.0 as discussed by the authors is a software package integrating several basic and advanced methods for population genetics data analysis, like the computation of standard genetic diversity indices, the estimation of allele and haplotype frequencies, tests of departure from linkage equilibrium, departure from selective neutrality and demographic equilibrium, estimation or parameters from past population expansions, and thorough analyses of population subdivision under the AMOVA framework.
Journal ArticleDOI
Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data.
TL;DR: In this article, a framework for the study of molecular variation within a single species is presented, where information on DNA haplotype divergence is incorporated into an analysis of variance format, derived from a matrix of squared-distances among all pairs of haplotypes.
Journal Article
Analysis of molecular variance inferred from metric distances among DNA haplotypes: application to human mitochondrial DNA restriction data.
Journal ArticleDOI
Principal components analysis corrects for stratification in genome-wide association studies
Alkes L. Price,Alkes L. Price,Nick Patterson,Robert M. Plenge,Robert M. Plenge,Michael E. Weinblatt,Nancy A. Shadick,David Reich,David Reich +8 more
TL;DR: This work describes a method that enables explicit detection and correction of population stratification on a genome-wide scale and uses principal components analysis to explicitly model ancestry differences between cases and controls.
References
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Journal ArticleDOI
Mendelian analysis of the pure breeds of livestock
Hugh C. Mcphee,Sewall Wright +1 more
Population structure in evolution.
TL;DR: It seems most probable that life and evolution began with the appearance of nucleoprotein molecules endowed with the remarkable capacity for autosynthesis, which obviously required an environment with a richness in organic compounds which could only have been arrived at in the prior absence of life.
Journal ArticleDOI
The amount of heterozygosis to be expected in an approximately pure line
TL;DR: It is calculated that in maize after 20 generations of self-fertilisation all but about 1 plant in 2500 is fully homozygous, but the average length of chromosome heterozygous in the exceptional plants is 2·5 units.
Related Papers (5)
Estimating F-statistics for the analysis of population structure.
Bruce S. Weir,C. Clark Cockerham +1 more