Open AccessJournal Article
The initial stages of template-controlled CaCO3 formation revealed by Cryo-TEM
TLDR
This paper showed that template-directed calcium carbonate formation starts with the formation of prenucleation clusters and their aggregation leads to the nucleation of amorphous nanoparticles in solution.Abstract:
Biogenic calcium carbonate forms the inorganic component of seashells, otoliths, and many marine skeletons, and its formation is directed by an ordered template of macromolecules. Classical nucleation theory considers crystal formation to occur from a critical nucleus formed by the assembly of ions from solution. Using cryotransmission electron microscopy, we found that template-directed calcium carbonate formation starts with the formation of prenucleation clusters. Their aggregation leads to the nucleation of amorphous nanoparticles in solution. These nanoparticles assemble at the template and, after reaching a critical size, develop dynamic crystalline domains, one of which is selectively stabilized by the template. Our findings have implications for template-directed mineral formation in biological as well as in synthetic systems.read more
Citations
More filters
疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A
TL;DR: PfPMP1）与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作�ly.
Journal ArticleDOI
Polydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental, and Biomedical Fields
Yanlan Liu,Kelong Ai,Lehui Lu +2 more
Journal ArticleDOI
Crystallization by particle attachment in synthetic, biogenic, and geologic environments
James J. De Yoreo,James J. De Yoreo,Pupa U. P. A. Gilbert,Pupa U. P. A. Gilbert,Nico A. J. M. Sommerdijk,R. Lee Penn,Stephen Whitelam,Derk Joester,Hengzhong Zhang,Jeffrey D. Rimer,Alexandra Navrotsky,Jillian F. Banfield,Adam F. Wallace,F. Marc Michel,Fiona C. Meldrum,Helmut Cölfen,Patricia M. Dove +16 more
TL;DR: The current understanding of CPA is described, some of the nonclassical thermodynamic and dynamic mechanisms known to give rise to experimentally observed pathways are examined, and the challenges to the understanding of these mechanisms are highlighted.
Journal ArticleDOI
The role of collagen in bone apatite formation in the presence of hydroxyapatite nucleation inhibitors
Fabio Nudelman,K. Pieterse,Anne George,Phh Paul Bomans,Heiner Friedrich,Laura J. Brylka,Peter A. J. Hilbers,Nico A. J. M. Sommerdijk +7 more
TL;DR: A model describing the mechanisms through which the structure, supramolecular assembly and charge distribution of collagen can control mineralization in the presence of inhibitors of hydroxyapatite nucleation is developed.
Journal ArticleDOI
Pre-nucleation clusters as solute precursors in crystallisation
TL;DR: In this review, classical nucleation theory, as well as established concepts of spinodal decomposition and liquid-liquid demixing, is introduced together with a description of the recently proposed pre-nucleation cluster pathway.
References
More filters
疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A
TL;DR: PfPMP1）与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作�ly.
Journal ArticleDOI
Polydopamine and Its Derivative Materials: Synthesis and Promising Applications in Energy, Environmental, and Biomedical Fields
Yanlan Liu,Kelong Ai,Lehui Lu +2 more
Journal ArticleDOI
Crystallization by particle attachment in synthetic, biogenic, and geologic environments
James J. De Yoreo,James J. De Yoreo,Pupa U. P. A. Gilbert,Pupa U. P. A. Gilbert,Nico A. J. M. Sommerdijk,R. Lee Penn,Stephen Whitelam,Derk Joester,Hengzhong Zhang,Jeffrey D. Rimer,Alexandra Navrotsky,Jillian F. Banfield,Adam F. Wallace,F. Marc Michel,Fiona C. Meldrum,Helmut Cölfen,Patricia M. Dove +16 more
TL;DR: The current understanding of CPA is described, some of the nonclassical thermodynamic and dynamic mechanisms known to give rise to experimentally observed pathways are examined, and the challenges to the understanding of these mechanisms are highlighted.
Journal ArticleDOI
Stable prenucleation calcium carbonate clusters.
TL;DR: It is demonstrated that dissolved calcium carbonate in fact contains stable prenucleation ion clusters forming even in undersaturated solution, and specified complex crystal structures challenge the classical view on nucleation considering the formation of metastable ion clusters.
Journal ArticleDOI
Molecular mechanistic origin of the toughness of natural adhesives, fibres and composites
Bettye L. Smith,Tilman E. Schäffer,Mario B. Viani,James B. Thompson,Neil A. Frederick,Johannes H. Kindt,Angela M. Belcher,Galen D. Stucky,Daniel E. Morse,Paul K. Hansma +9 more
TL;DR: In this article, the authors used the atomic force microscope to stretch the organic molecules exposed on the surface of freshly cleaved nacre and found that the elongation events occur for forces of a few hundred piconewtons, which are smaller than the forces of over a nanonewton required to break the polymer backbone in the threads.