Journal ArticleDOI
The prevalence and risk factors of retinal microvascular abnormalities in older persons: the Cardiovascular Health Study☆
Tien Yin Wong,Tien Yin Wong,Ronald Klein,A. Richey Sharrett,Teri A. Manolio,Larry D. Hubbard,Emily K Marino,Lewis H. Kuller,Gregory L. Burke,Russell P. Tracy,Joseph F. Polak,John S. Gottdiener,David S. Siscovick +12 more
Reads0
Chats0
TLDR
It is suggested that retinal microvascular abnormalities reflect processes associated with hypertension but distinct from atherosclerosis, and are common in older persons without diabetes and related to hypertension.About:
This article is published in Ophthalmology.The article was published on 2003-04-01. It has received 295 citations till now. The article focuses on the topics: Arteriovenous nicking & Retinopathy.read more
Citations
More filters
Journal ArticleDOI
Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure
Aram V. Chobanian,George L. Bakris,Henry R. Black,William C. Cushman,Lee A. Green,Joseph L. Izzo,Daniel W. Jones,Barry J. Materson,Suzanne Oparil,Jackson T. Wright,Edward J. Roccella +10 more
TL;DR: In those older than age 50, systolic blood pressure of greater than 140 mm Hg is a more important cardiovascular disease (CVD) risk factor than diastolic BP, and hypertension will be controlled only if patients are motivated to stay on their treatment plan.
Journal ArticleDOI
Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures
TL;DR: The anatomical and physiological homology between the retinal and cerebral microvasculatures is described and the evidence that retinal microvascular changes occur in cerebrovascular disease is reviewed.
Journal ArticleDOI
Retinal image analysis: Concepts, applications and potential
Niall Patton,Tariq Aslam,Tom MacGillivray,Ian J. Deary,B. Dhillon,Robert H. Eikelboom,Robert H. Eikelboom,Kanagasingam Yogesan,Ian J. Constable +8 more
TL;DR: The use of image analysis in the automated diagnosis of pathology (with particular reference to diabetic retinopathy) is reviewed, as well as its role in defining and performing quantitative measurements of vascular topography, and how these entities are based on 'optimisation' principles.
Journal ArticleDOI
Retinal Vascular Caliber, Cardiovascular Risk Factors, and Inflammation: The Multi-Ethnic Study of Atherosclerosis (MESA)
Tien Yin Wong,Tien Yin Wong,F.M. Amirul Islam,Ronald Klein,Barbara E.K. Klein,Mary Frances Cotch,Cecilia Castro,A. Richey Sharrett,Eyal Shahar +8 more
TL;DR: Retinal arteriolar and venular caliber is associated with a range of cardiovascular risk factors, including hypertension, diabetes, measures of obesity, and dyslipidemia and is also associated with systemic inflammation.
Journal ArticleDOI
The eye in hypertension.
Tien Yin Wong,Paul Mitchell +1 more
TL;DR: Recognition of the ocular effects of blood pressure could allow physicians to better manage patients with hypertension, and to monitor its end-organ effects.
References
More filters
Journal ArticleDOI
The measurement of observer agreement for categorical data
J. R. Landis,Gary G. Koch +1 more
TL;DR: A general statistical methodology for the analysis of multivariate categorical data arising from observer reliability studies is presented and tests for interobserver bias are presented in terms of first-order marginal homogeneity and measures of interob server agreement are developed as generalized kappa-type statistics.
Journal ArticleDOI
Carotid-Artery Intima and Media Thickness as a Risk Factor for Myocardial Infarction and Stroke in Older Adults
Daniel H. O'Leary,Joseph F. Polak,Richard A. Kronmal,Teri A. Manolio,Gregory L. Burke,Sidney K. Wolfson +5 more
TL;DR: Increases in the thickness of the intima and media of the carotid artery, as measured noninvasively by ultrasonography, are directly associated with an increased risk of myocardial infarction and stroke in older adults without a history of cardiovascular disease.
Journal ArticleDOI
The cardiovascular health study: Design and rationale
Linda P. Fried,Nemat O. Borhani,Paul L. Enright,Curt D. Furberg,Julius M. Gardin,Richard A. Kronmal,Lewis H. Kuller,Teri A. Manolio,Maurice B. Mittelmark,Anne B. Newman,Daniel H. O'Leary,Bruce M. Psaty,Pentti M. Rautaharju,Russell P. Tracy,Philip G. Weiler +14 more
TL;DR: These examinations in CHS permit evaluation of CVD risk factors in older adults, particularly in groups previously under-represented in epidemiologic studies, such as women and the very old.
Journal ArticleDOI
The Beaver Dam Eye Study. Retinopathy in adults with newly discovered and previously diagnosed diabetes mellitus.
TL;DR: The prevalence of diabetic retinopathy was examined in people with newly discovered noninsulin-dependent diabetes mellitus (NIDDM) (n = 50) and in those with previously diagnosed diabetes.
Journal ArticleDOI
Ankle-arm index as a marker of atherosclerosis in the Cardiovascular Health Study. Cardiovascular Heart Study (CHS) Collaborative Research Group.
Anne B. Newman,David S. Siscovick,Teri A. Manolio,Joseph F. Polak,Linda P. Fried,Nemat O. Borhani,Sidney K. Wolfson +6 more
TL;DR: There was an inverse dose-response relation of the AAI with CVD risk factors and subclinical and clinical CVD among older adults, and even those with modest, asymptomatic reductions in theAAI appear to be at increased risk of CVD.