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Open AccessJournal ArticleDOI

The Semantic Automated Discovery and Integration (SADI) Web service Design-Pattern, API and Reference Implementation

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TLDR
The SADI design patterns significantly improve the ability of software to automatically discover appropriate services based on user-needs, and automatically chain these into complex analytical workflows, thus facilitating the intersection of Web services and Semantic Web technologies.
Abstract
The complexity and inter-related nature of biological data poses a difficult challenge for data and tool integration. There has been a proliferation of interoperability standards and projects over the past decade, none of which has been widely adopted by the bioinformatics community. Recent attempts have focused on the use of semantics to assist integration, and Semantic Web technologies are being welcomed by this community. SADI - Semantic Automated Discovery and Integration - is a lightweight set of fully standards-compliant Semantic Web service design patterns that simplify the publication of services of the type commonly found in bioinformatics and other scientific domains. Using Semantic Web technologies at every level of the Web services "stack", SADI services consume and produce instances of OWL Classes following a small number of very straightforward best-practices. In addition, we provide codebases that support these best-practices, and plug-in tools to popular developer and client software that dramatically simplify deployment of services by providers, and the discovery and utilization of those services by their consumers. SADI Services are fully compliant with, and utilize only foundational Web standards; are simple to create and maintain for service providers; and can be discovered and utilized in a very intuitive way by biologist end-users. In addition, the SADI design patterns significantly improve the ability of software to automatically discover appropriate services based on user-needs, and automatically chain these into complex analytical workflows. We show that, when resources are exposed through SADI, data compliant with a given ontological model can be automatically gathered, or generated, from these distributed, non-coordinating resources - a behaviour we have not observed in any other Semantic system. Finally, we show that, using SADI, data dynamically generated from Web services can be explored in a manner very similar to data housed in static triple-stores, thus facilitating the intersection of Web services and Semantic Web technologies.

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Citations
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Journal ArticleDOI

EDAM: an ontology of bioinformatics operations, types of data and identifiers, topics and formats

TL;DR: EDAM is an ontology of bioinformatics operations (tool or workflow functions), types of data and identifiers, application domains and data formats, which supports semantic annotation of diverse entities such as Web services, databases, programmatic libraries, standalone tools, interactive applications, data schemas, datasets and publications within bio informatics.
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Text-mining solutions for biomedical research: enabling integrative biology.

TL;DR: The latest advancements in automated literature analysis are explored and its contribution to innovative research approaches are explored.
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PubChemRDF: towards the semantic annotation of PubChem compound and substance databases

TL;DR: An approach to translate PubChem Substance and Compound information into Resource Description Framework (RDF) format was described, with the goal of semantically describing information available in the PubChem archive, pre-existing ontological frameworks were used, rather than creating new ones.
References
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Journal ArticleDOI

Linked Data - the story so far

TL;DR: The authors describe progress to date in publishing Linked Data on the Web, review applications that have been developed to exploit the Web of Data, and map out a research agenda for the Linked data community as it moves forward.
Proceedings Article

DAML-S: semantic markup for web services

TL;DR: The overall structure of the ontology, the service profile for advertising services, and the process model for the detailed description of the operation of services are described, which compare DAML-S with several industry efforts to define standards for characterizing services on the Web.
Journal ArticleDOI

Pellet: A practical OWL-DL reasoner

TL;DR: Pellet is the first sound and complete OWL-DL reasoner with extensive support for reasoning with individuals, user-defined datatypes, and debugging support for ontologies.
Journal ArticleDOI

Taverna: a tool for the composition and enactment of bioinformatics workflows

TL;DR: The Taverna project has developed a tool for the composition and enactment of bioinformatics workflows for the life sciences community that is written in a new language called Scufl, where by each step within a workflow represents one atomic task.
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