Journal ArticleDOI
The size of solid lipid nanoparticles: an interpretation from experimental design.
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TLDR
SLN were able to entrap a high amount of simvastatin, with little effect upon size and zeta potential, constituting a promising carrier for lipophilic drugs.About:
This article is published in Colloids and Surfaces B: Biointerfaces.The article was published on 2011-05-01. It has received 137 citations till now. The article focuses on the topics: Solid lipid nanoparticle & Particle size.read more
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Recent advances on polysaccharides, lipids and protein based edible films and coatings: A review.
Bilal Hassan,Shahzad Ali Shahid Chatha,Abdullah Ijaz Hussain,Khalid Mahmood Zia,Naseem Akhtar +4 more
TL;DR: Edible films and coatings are thin layers applied on food products to protect them from microbial growth, prolonging their shelf life and improving other quality aspects like sensory attributes, appearance, originality and freshness of ingredients.
Journal ArticleDOI
Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release
TL;DR: The importance of obtaining a detailed knowledge of the structure of the lipid nanoparticles is highlighted, which is useful for the rational design of this type of nanocarriers and propose solutions to the challenges involved in their formulation.
Journal ArticleDOI
Solid lipid nanoparticles: an oral bioavailability enhancer vehicle.
TL;DR: The protective effect of SLNs, coupled with their sustained/controlled release properties, prevents drugs/macromolecules from premature degradation and improves their stability in the GIT, and make SLNs a potential BA enhancer vehicle for various Class II, III and IV drugs.
Journal ArticleDOI
Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease.
TL;DR: A systematic review of nanotechnology-based drug delivery systems for the treatment of Alzheimer’s disease finds each are promising tools for the delivery of therapeutic devices to the brain via various routes of administration, particularly the intranasal route.
Optimisation and stability assessment of solid lipid nanoparticles using particle size and zeta potential
TL;DR: In this article, the physicochemical properties such as particle size, polydispersity index (PI) and zeta potential are evaluated for solid lipid nanoparticles (SLNs) in order to understand the influence of variation in SLN composition (lipid and emulsifier concentration).
References
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Journal ArticleDOI
Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art.
TL;DR: Relevant issues for the introduction of SLN to the pharmaceutical market, such as status of excipients, toxicity/tolerability aspects and sterilization and long-term stability including industrial large scale production are discussed.
Journal ArticleDOI
Solid lipid nanoparticles: Production, characterization and applications
W. Mehnert,Karsten Mäder +1 more
TL;DR: An overview about the selection of the ingredients, different ways of SLN production and SLN applications, and the in vivo fate of the carrier are presented.
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Nanosuspensions in drug delivery
TL;DR: Water insolubility issues of the past have provoked a paradigm change, which now offers novel solutions for innovative drugs of the future, and additional pharmacokinetic benefits of the drugs so formulated have come to be appreciated.
Journal ArticleDOI
Solid lipid nanoparticles for parenteral drug delivery.
TL;DR: The biological activity of parenterally applied SLN and biopharmaceutical aspects such as pharmacokinetic profiles as well as toxicity aspects are reviewed.
Journal ArticleDOI
Design and Production of Nanoparticles Formulated From Nano-Emulsion Templates-A Review
TL;DR: A link between nano-emulsion formulation methods and nanoparticle generation is proposed, while at the same time bearing in mind the above-mentioned parameters for active molecule encapsulation.
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