The structural and functional connectivity of the amygdala: From normal emotion to pathological anxiety
M. Justin Kim,Rebecca A. Loucks,Amy L. Palmer,Annemarie C. Brown,Kimberly M. Solomon,Ashley N. Marchante,Paul J. Whalen +6 more
TLDR
The capacity for efficient crosstalk between the amygdala and the mPFC, which is represented as the strength of the amygdala-mPFC circuitry, is crucial to beneficial outcomes in terms of reported anxiety.About:
This article is published in Behavioural Brain Research.The article was published on 2011-10-01 and is currently open access. It has received 742 citations till now. The article focuses on the topics: Anxiety disorder & Extinction (psychology).read more
Citations
More filters
Journal ArticleDOI
Sources of Method Bias in Social Science Research and Recommendations on How to Control It
TL;DR: The meaning of the terms "method" and "method bias" are explored and whether method biases influence all measures equally are examined, and the evidence of the effects that method biases have on individual measures and on the covariation between different constructs is reviewed.
Journal ArticleDOI
Fear Extinction as a Model for Translational Neuroscience: Ten Years of Progress
TL;DR: Research in fear extinction could serve as a model for translational research in other areas of behavioral neuroscience, and new approaches to understanding and exploiting fear extinction are highlighted.
Journal ArticleDOI
Early developmental emergence of human amygdala-prefrontal connectivity after maternal deprivation.
Dylan G. Gee,Laurel J. Gabard-Durnam,Jessica Flannery,Bonnie Goff,Kathryn L. Humphreys,Eva H. Telzer,Todd A. Hare,Susan Y. Bookheimer,Nim Tottenham +8 more
TL;DR: It is demonstrated that, as in the rodent, children who experienced early maternal deprivation exhibit early emergence of mature amygdala–prefrontal connectivity, suggesting that accelerated amygdala–mPFC development is an ontogenetic adaptation in response to early adversity.
Journal ArticleDOI
A Developmental Shift from Positive to Negative Connectivity in Human Amygdala-Prefrontal Circuitry
Dylan G. Gee,Kathryn L. Humphreys,Jessica Flannery,Bonnie Goff,Eva H. Telzer,Mor Shapiro,Todd A. Hare,Susan Y. Bookheimer,Nim Tottenham +8 more
TL;DR: Results suggest positive amygdala–prefrontal connectivity in early childhood that switches to negative functional connectivity during the transition to adolescence, and initial positive connectivity followed by a valence shift to negative connectivity provides a neurobiological basis for regulatory development.
Journal ArticleDOI
The Role of Emotion Regulation in Autism Spectrum Disorder
Carla A. Mazefsky,John D. Herrington,Matthew Siegel,Angela Scarpa,Brenna B. Maddox,Lawrence Scahill,Susan W. White +6 more
TL;DR: Poor ER may be inherent in ASD and may provide a more parsimonious conceptualization for the many associated socioemotional and behavioral problems in this population.
References
More filters
Journal ArticleDOI
Diagnostic and Statistical Manual of Mental Disorders
Vijay A. Mittal,Elaine F. Walker +1 more
TL;DR: An issue concerning the criteria for tic disorders is highlighted, and how this might affect classification of dyskinesias in psychotic spectrum disorders.
Journal ArticleDOI
Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States: Results From the National Comorbidity Survey
Ronald C. Kessler,Katherine A. McGonagle,Shanyang Zhao,Christopher B. Nelson,Michael R. Hughes,Suzann Eshleman,Hans-Ulrich Wittchen,Kenneth S. Kendler +7 more
TL;DR: The prevalence of psychiatric disorders is greater than previously thought to be the case, and morbidity is more highly concentrated than previously recognized in roughly one sixth of the population who have a history of three or more comorbid disorders.
Journal ArticleDOI
An integrative theory of prefrontal cortex function
Earl K. Miller,Jonathan D. Cohen +1 more
TL;DR: It is proposed that cognitive control stems from the active maintenance of patterns of activity in the prefrontal cortex that represent goals and the means to achieve them, which provide bias signals to other brain structures whose net effect is to guide the flow of activity along neural pathways that establish the proper mappings between inputs, internal states, and outputs needed to perform a given task.
Journal ArticleDOI
Functional connectivity in the motor cortex of resting human brain using echo-planar MRI.
TL;DR: It is concluded that correlation of low frequency fluctuations, which may arise from fluctuations in blood oxygenation or flow, is a manifestation of functional connectivity of the brain.
Related Papers (5)
Functional Neuroimaging of Anxiety: A Meta-Analysis of Emotional Processing in PTSD, Social Anxiety Disorder, and Specific Phobia
Amit Etkin,Tor D. Wager +1 more