Open AccessJournal Article
Therapeutic applications of fenugreek.
TLDR
Preliminary animal and human trials suggest possible hypoglycemic and antihyperlipidemic properties of oral fenugreek seed powder.Abstract:
Fenugreek has a long history of medical uses in Ayurvedic and Chinese medicine, and has been used for numerous indications, including labor induction, aiding digestion, and as a general tonic to improve metabolism and health. Preliminary animal and human trials suggest possible hypoglycemic and antihyperlipidemic properties of oral fenugreek seed powder. (Altern Med Rev 2003;8(1):20-27)read more
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Catalytic degradation of organic dyes using biosynthesized silver nanoparticles.
V.K. Vidhu,Daizy Philip +1 more
TL;DR: An environmentally benign and unexploited method for the synthesis of silver nanocatalysts using Trigonella foenum-graecum seeds, which is a potential source of phytochemicals is reported.
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Natural Products for the Treatment of Type 2 Diabetes Mellitus
TL;DR: This review compiles the principal articles on medicinal plants used for treating diabetes and its comorbidities, as well as mechanisms of natural products as antidiabetic agents, and considers compounds of high interest as potential antidiabetics.
Journal Article
Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells
TL;DR: Results from the in vitro experiments indicated that diosgenin inhibits cell growth and induces apoptosis in the HT-29 human colon cancer cell line in a dose-dependent manner and seems to have potential as a novel colon cancer preventive agent.
Journal ArticleDOI
In vitro studies on antiradical and antioxidant activities of fenugreek (Trigonella foenum graecum) seeds
TL;DR: In this paper, an extract of fenugreek (Trigonella foenum graecum) seeds was isolated and evaluated for antioxidant activity using various in vitro assay systems.
Journal ArticleDOI
Trigonelline: a plant alkaloid with therapeutic potential for diabetes and central nervous system disease.
Jiyin Zhou,L. Chan,S. Zhou +2 more
TL;DR: Because of its pharmacological value and low toxicity, the reported adverse effects of trigonelline in experimental animal models and humans are briefly reviewed, and the pharmacokinetics of trig onelline are also discussed.
References
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Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Scott M. Grundy,David W. Bilheimer,Alan Chait,Luther T. Clark,Margo A. Denke,Richard J. Havel,William R. Hazzard,Stephen B. Hulley,Donald B. Hunninghake,Robert A. Kreisberg,Penny M. Kris-Etherton,James M. McKenney,Michael A. Newman,Ernst J. Schaefer,Burton E. Sobel,Carolyn Somelofski,Milton C. Weinstein,H. Bryan Brewer,James I. Cleeman,Karen A. Donato,Nancy D. Ernst,Jeffrey M. Hoeg,Basil M. Rifkind,Jacques E. Rossouw,Christopher T. Sempos,Joanne M. Gallivan,Maureen N. Harris,Laurie Quint-Adler +27 more
TL;DR: Dairy therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD, and the fundamental approach to treatment is comparable.
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Prevalence of the Metabolic Syndrome Among US Adults: Findings From the Third National Health and Nutrition Examination Survey
TL;DR: These results from a representative sample of US adults show that the metabolic syndrome is highly prevalent and the large numbers of US residents with the metabolic Syndrome may have important implications for the health care sector.
Journal Article
Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes.
TL;DR: Results indicate the usefulness of fenugreek seeds in the management of diabetes and significantly reduced fasting blood sugar and improved the glucose tolerance test.
Journal ArticleDOI
Effect of ginger (Zingiber officinale Rosc.) and fenugreek (Trigonella foenumgraecum L.) on blood lipids', blood sugar and platelet aggregation in patients with coronary artery disease
TL;DR: In patients with CAD powdered ginger administered in a dose of 4 g daily for 3 months did not affect ADP- and epinephrine-induced platelet aggregation, and no change in the fibrinolytic activity and fibrinogen level was observed.
Journal ArticleDOI
4-Hydroxyisoleucine: A Novel Amino Acid Potentiator of Insulin Secretion
Yves Sauvaire,Pierre Petit,Christophe Broca,M. Manteghetti,Yves Baissac,Josepha Fernandez-Alvarez,René Gross,M. Roye,Agnès Leconte,Ramon Gomis,Gérard Ribes +10 more
TL;DR: 4-hydroxyisoleucine insulinotropic activity might, at least in part, account for fenugreek seeds' antidiabetic properties and may be considered as a novel drug with potential interest for the treatment of NIDDM.