Journal ArticleDOI
Two different chromatin structures coexist in ribosomal RNA genes throughout the cell cycle
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TLDR
It is shown that in intact cells, two distinct types of ribosomal chromatin coexist in Friend cells, one that contains nucleosomes and represents the inactive copies and one that lacks a repeating structure and corresponds to the transcribed genes.About:
This article is published in Cell.The article was published on 1989-06-02. It has received 376 citations till now. The article focuses on the topics: Chromatin & Solenoid (DNA).read more
Citations
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Nutritional Control of Growth and Development in Yeast
TL;DR: The current understanding of the structures of the networks responsible for assessing the quantity and quality of carbon and nitrogen sources are reviewed and the profound knowledge on the structure of these signaling networks are highlighted.
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Salicylic acid inhibits synthesis of proteinase inhibitors in tomato leaves induced by systemin and jasmonic acid
TL;DR: The inhibition of synthesis of proteinase inhibitor proteins and mRNAs by SA in both light and darkness also occurs at a step in the signal transduction pathway, after JA synthesis but preceding transcription of the inhibitor genes.
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Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus
TL;DR: This review restricts the background information to the minimal level that is required for understanding initiation complex formation at the rDNA promoter before proceeding to review the regulatory pathways that adapt cellular rRNA synthesis to cell metabolism and growth.
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SURVEY AND SUMMARY Transcription by RNA polymerases I and III
Marvin R. Paule,Robert J. White +1 more
TL;DR: This survey will summarise what is known about the process of transcription by pol I and pol III, how it happens and the proteins involved and attention will be drawn to the similarities between the three nuclear RNA polymerase systems and also to their differences.
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The Epigenetics of rRNA Genes: From Molecular to Chromosome Biology
Brian McStay,Ingrid Grummt +1 more
TL;DR: This chapter summarizes the knowledge of the molecular mechanisms that establish and propagate the epigenetic state of rRNA genes, unraveling a complex interplay of DNA methyltransferases and histone-modifying enzymes that act in concert with chromatin remodeling complexes and RNA-guided mechanisms to define the transcriptional state ofrDNA.
References
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Genomic sequencing
George M. Church,Walter Gilbert +1 more
TL;DR: The genomic sequencing procedures are applicable to the analysis of genetic polymorphisms, DNA methylation at deoxycytidines, and nucleic acid-protein interactions at single nucleotide resolution.
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Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.
TL;DR: Ten percent dextran sulfate accelerates the rate of hybridization of randomly cleaved double-stranded DNA probes to immobilized nucleic acids by as much as 100-fold, without increasing the background significantly.
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Removal of positioned nucleosomes from the yeast PHO5 promoter upon PHO5 induction releases additional upstream activating DNA elements.
TL;DR: The chromatin fine structure in the promoter region of PHO5, the structural gene for a strongly regulated acid phosphatase in yeast, was analyzed and a mechanism by which the chromatin structure participates in the functioning of a regulated promoter is suggested.
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Transcriptionally active chromatin.
TL;DR: Eukaryotic chromatin has a dynamic, complex hierarchical structure and the chromatin structure of various DNA regulatory sequences, such as promoters, terminators and enhancers, appears to partially regulate transcriptional activity.
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Structure of replicating simian virus 40 minichromosomes: The replication fork, core histone segregation and terminal structures☆
TL;DR: The structure of replicating simian virus 40 (SV40) minichromosomes was studied by DNA crosslinking with trimethyl-psoralen and a novel type of interlocked dimer comprising two fully replicated molecules connected by a single-stranded DNA bridge was detected.