Journal ArticleDOI
Visual cocaine detection with gold nanoparticles and rationally engineered aptamer structures
TLDR
A novel bioassay strategy is designed to detect small-molecule targets such as cocaine, potassium, and adenosine, based on gold nanoparticles (AuNPs) and engineered DNA aptamers, which is shown to be generic and applicable to the detection of several other small-mitecule targets.Abstract:
A novel bioassay strategy is designed to detect small-molecule targets such as cocaine, potassium, and adenosine, based on gold nanoparticles (AuNPs) and engineered DNA aptamers. In this design, an aptamer is engineered to be two pieces of random, coil-like single-stranded DNA, which reassembles into the intact aptamer tertiary structure in the presence of the specific target. AuNPs can effectively differentiate between these two states via their characteristic surface-plasmon resonance-based color change. Using this method, cocaine in the low-micromolar range is selectively detected within minutes. This strategy is also shown to be generic and applicable to the detection of several other small-molecule targets.read more
Citations
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Gold nanoparticles in biomedical applications: recent advances and perspectives
TL;DR: This critical review is focused on the application of GNP conjugates to biomedical diagnostics and analytics, photothermal and photodynamic therapies, and delivery of target molecules.
Journal ArticleDOI
Applications of nanotechnology in food packaging and food safety: Barrier materials, antimicrobials and sensors
TL;DR: Several applications of nanomaterials in food packaging and food safety are reviewed, including polymer/clay nanocomposites as high barrier packaging materials, silver nanoparticles as potent antimicrobial agents, and nanosensors and nanomMaterial-based assays for the detection of food-relevant analytes.
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Gold Nanomaterials at Work in Biomedicine
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LSPR-based nanobiosensors
TL;DR: The basis behind LSPR sensing is described, the latest progress regarding nanostructure fabrication techniques and biosensing applications are summarized, and the challenges that L SPR biosensors should face are discussed.
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