Water-mediated structuring of bone apatite
Yan Wang,Stanislas Von Euw,Francisco M. Fernandes,Sophie Cassaignon,Mohamed Selmane,Guillaume Laurent,Gérard Pehau-Arnaudet,Cristina Coelho,Laure Bonhomme-Coury,Marie-Madeleine Giraud-Guille,Florence Babonneau,Thierry Azaïs,Nadine Nassif +12 more
TLDR
It is demonstrated that water orients apatite crystals through an amorphous calcium phosphate-like layer that coats the crystalline core of bone Apatite, providing an extended local model of bone biomineralization.Abstract:
It is well known that organic molecules from the vertebrate extracellular matrix of calcifying tissues are essential in structuring the apatite mineral. Here, we show that water also plays a structuring role. By using solid-state nuclear magnetic resonance, wide-angle X-ray scattering and cryogenic transmission electron microscopy to characterize the structure and organization of crystalline and biomimetic apatite nanoparticles as well as intact bone samples, we demonstrate that water orients apatite crystals through an amorphous calcium phosphate-like layer that coats the crystalline core of bone apatite. This disordered layer is reminiscent of those found around the crystalline core of calcified biominerals in various natural composite materials in vivo. This work provides an extended local model of bone biomineralization.read more
Citations
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Calcium Phosphate Bioceramics: A Review of Their History, Structure, Properties, Coating Technologies and Biomedical Applications.
Noam Eliaz,Noah Metoki +1 more
TL;DR: A wide variety of CaPs are presented, from the individual phases to nano-CaP, biphasic and triphasic CaP formulations, composite CaP coatings and cements, functionally graded materials (FGMs), and antibacterial CaPs.
Journal ArticleDOI
Bone hierarchical structure in three dimensions
TL;DR: A new hierarchical scheme for several bone tissue types that incorporates these two materials, the major material being the well-known ordered arrays of mineralized collagen fibrils and associated macromolecules, and the minor component being a relatively disordered material.
Journal ArticleDOI
Fractal-like hierarchical organization of bone begins at the nanoscale
TL;DR: Higher-level bone mineral organization within the extracellular matrix is studied by means of scanning TEM tomography imaging and 3D reconstruction, as well as electron diffraction to determine crystal morphology and orientation patterns, which resulted in a model of 3D mineral morphology and its association with the organic matrix.
Journal ArticleDOI
Induction of long-lived room temperature phosphorescence of carbon dots by water in hydrogen-bonded matrices
TL;DR: A strategy for the long-lived phosphorescence of carbon dots in water due to multiple hydrogen-bonding interactions is presented, which exhibits a high phosphorescence lifetime (687 ms) and is successfully applied in ion detection based on its visible phosphorescence.
Journal ArticleDOI
Hierarchical Structures of Bone and Bioinspired Bone Tissue Engineering.
TL;DR: This critical review provides a broad overview of the current mechanisms involved in bone biomineralization, and the relationship between bone hierarchical structures and the deformation mechanism.
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