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Aaron J. Peoples

Researcher at NovoBiotic Pharmaceuticals

Publications -  23
Citations -  2467

Aaron J. Peoples is an academic researcher from NovoBiotic Pharmaceuticals. The author has contributed to research in topics: Lipid II & Antibiotics. The author has an hindex of 8, co-authored 20 publications receiving 2065 citations.

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A new antibiotic kills pathogens without detectable resistance

TL;DR: The properties of this compound suggest a path towards developing antibiotics that are likely to avoid development of resistance, as well as several methods to grow uncultured organisms by cultivation in situ or by using specific growth factors.
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Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2

TL;DR: It is shown that lassomycin binds to a highly acidic region of the ClpC1 ATPase complex and markedly stimulates its ATPase activity without stimulating ClpP1P2-catalyzed protein breakdown, which is essential for viability of mycobacteria.
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Neocitreamicins I and II, Novel Antibiotics with Activity against Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci

TL;DR: Two novel antibiotics, neocitreamicins I and II, were isolated from a fermentation broth of a Nocardia strain and showed in vitro activity against Gram-positive bacteria including strains of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis.
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Erratum: A new antibiotic kills pathogens without detectable resistance

TL;DR: This corrects the article to show that the Higgs boson genome is a “spatially aggregated “vessel” rather than an “ aggregating “ nucleus”, which indicates that theorems related to “consolidation” and “ghosting” are more likely to occur.