Dallas Hughes

TL;DR: The properties of this compound suggest a path towards developing antibiotics that are likely to avoid development of resistance, as well as several methods to grow uncultured organisms by cultivation in situ or by using specific growth factors.

TL;DR: It is shown that lassomycin binds to a highly acidic region of the ClpC1 ATPase complex and markedly stimulates its ATPase activity without stimulating ClpP1P2-catalyzed protein breakdown, which is essential for viability of mycobacteria.

TL;DR: This corrects the article to show that the Higgs boson genome is a “spatially aggregated “vessel” rather than an “ aggregating “ nucleus”, which indicates that theorems related to “consolidation” and “ghosting” are more likely to occur.

TL;DR: The authors employed affinity capillary electrophoresis (ACE) to identify antimicrobial compounds that bound the novel target YihA and validate ACE as a valuable tool for the fast, efficient detection of specific binding molecules that possess biological activity.

TL;DR: The mechanism of Teixobactin at the atomic level using a combination of solid-state NMR, microscopy, in vivo assays and molecular dynamics simulations was revealed in this paper .