Alexia Ferrand

TL;DR: An overview of current super-resolution microscopy techniques is given and guidance on how best to use them to foster biological discovery is provided.

TL;DR: It is proposed that the spatial disconnection between end resection and RAD51 binding prevents the activation of mutagenic pathways and illegitimate recombination and suggests a model in which the commitment to specific DNA repair pathways regulates DSB position.

TL;DR: Considering the large panel of available antibodies and the simplicity of their implementation, VANIMA can be used to uncover novel biological information based on the dynamic behavior of transcription factors or posttranslational modifications in the nucleus of single live cells.

TL;DR: In Drosophila neuroblasts, the mitotic spindle, but not polarity cues, controls the localization of the CPC component Survivin, and it is shown that Survivin and the spindle are required to stabilize the position of the cleavage furrow in late anaphase and to complete furrow constriction.

TL;DR: The QUAREP-LiMi project as mentioned in this paper aims to improve reproducibility for light microscopy image data through quality control (QC) management of instruments and images through a common set of QC guidelines for hardware calibration and image acquisition, management and analysis.