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Emmanuel Buschiazzo

Researcher at University of British Columbia

Publications -  20
Citations -  1566

Emmanuel Buschiazzo is an academic researcher from University of British Columbia. The author has contributed to research in topics: Genome & Microsatellite. The author has an hindex of 11, co-authored 20 publications receiving 1453 citations. Previous affiliations of Emmanuel Buschiazzo include University of California, Merced & International Atomic Energy Agency.

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Journal ArticleDOI

Genome analysis of the platypus reveals unique signatures of evolution

Wesley C. Warren, +104 more
- 08 May 2008 - 
TL;DR: It is found that reptile and platypus venom proteins have been co-opted independently from the same gene families; milk protein genes are conserved despite platypuses laying eggs; and immune gene family expansions are directly related to platypUS biology.
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The rise, fall and renaissance of microsatellites in eukaryotic genomes.

TL;DR: This review provides an up-to-date account of the mutational processes, biases and constraints believed to be involved in the evolution of microsatellites, particularly with respect to the creation and degeneration of micro satellite sequences, which it is asserted may be broadly viewed as a life cycle.
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Microsatellite tandem repeats are abundant in human promoters and are associated with regulatory elements.

TL;DR: The results suggest that many promoter microsatellites have the potential to affect human phenotypes by generating mutations in regulatory elements, which may ultimately result in disease.
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Slow but not low: genomic comparisons reveal slower evolutionary rate and higher dN/dS in conifers compared to angiosperms.

TL;DR: It is proposed that reduced levels of nucleotide mutation in large and long-lived conifer trees, coupled with large effective population size, were the main factors leading to slow substitution rates but retention of beneficial mutations.