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Anand Swaroop
Researcher at National Institutes of Health
Publications - 528
Citations - 53580
Anand Swaroop is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Retinitis pigmentosa & Retinal degeneration. The author has an hindex of 89, co-authored 508 publications receiving 43170 citations. Previous affiliations of Anand Swaroop include Vision-Sciences, Inc. & Yale University.
Papers
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Journal ArticleDOI
Phenotypes in three Swedish families with X-linked retinitis pigmentosa caused by different mutations in the RPGR gene
Sten Andréasson,Vesna Ponjavic,Magnus Abrahamson,Berndt Ehinger,Weiping Wu,Ricardo Fujita,M. Buraczynska,Anand Swaroop +7 more
TL;DR: These three families show a variable clinical phenotype resulting from different mutations in the RPGR gene, with a microdeletion spanning at least parts of exons 8 through 10 seems to result in a severe phenotype compared to the splice defects.
Journal ArticleDOI
Generation of H2O2 in brain mitochondria.
TL;DR: Brain mitochondria from rabbit, hamster, mouse, and guinea pig also have the capacity to generate H2O2 on oxidation of glycerol‐l‐phosphate and this activity was found to be maximal in cerebellum.
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Pharmacologic fibroblast reprogramming into photoreceptors restores vision.
Biraj Mahato,Koray Dogan Kaya,Yan Fan,Nathalie Sumien,Ritu A. Shetty,Wei Zhang,Delaney L Davis,Thomas Thomas Mock,Subrata Batabyal,Aiguo Ni,Samarendra K. Mohanty,Zongchao Han,Rafal Farjo,Michael J. Forster,Anand Swaroop,Sai H. Chavala +15 more
TL;DR: A set of five small molecules can induce the transformation of fibroblasts into rod photoreceptor-like cells, which can partially restore pupil reflex and visual function when transplanted into a rod degeneration mouse model.
Journal ArticleDOI
Associations of CFHR1-CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent.
Soumya Raychaudhuri,Soumya Raychaudhuri,Soumya Raychaudhuri,Stephan Ripke,Stephan Ripke,Mingyao Li,Benjamin M. Neale,Benjamin M. Neale,Benjamin M. Neale,Jesen Fagerness,Jesen Fagerness,Robyn Reynolds,Lucia Sobrin,Anand Swaroop,Gonçalo R. Abecasis,Johanna M. Seddon,Mark J. Daly,Mark J. Daly +17 more
TL;DR: Associations of CFHR1–CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent.
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Vision from next generation sequencing: multi-dimensional genome-wide analysis for producing gene regulatory networks underlying retinal development, aging and disease.
TL;DR: This review discusses NGS-based genome-wide approaches that can provide deeper insights into retinal development, aging and disease pathogenesis and discuss NGS technology in the context of retinal disease and develops a vision for therapies based on network biology.