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Anand Swaroop
Researcher at National Institutes of Health
Publications - 528
Citations - 53580
Anand Swaroop is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Retinitis pigmentosa & Retinal degeneration. The author has an hindex of 89, co-authored 508 publications receiving 43170 citations. Previous affiliations of Anand Swaroop include Vision-Sciences, Inc. & Yale University.
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Journal ArticleDOI
Cone-rod homeobox CRX controls presynaptic active zone formation in photoreceptors of mammalian retina
Juthaporn Assawachananont,Soo-Young Kim,Koray Dogan Kaya,Robert N. Fariss,Jerome E. Roger,Jerome E. Roger,Anand Swaroop +6 more
TL;DR: It is demonstrated that CRX controls the establishment of CAZ and anchoring of ribbons, but not the formation of ribbon itself, in photoreceptor presynaptic terminals.
Journal ArticleDOI
Gene-Based Association Analysis for Censored Traits Via Fixed Effect Functional Regressions.
Ruzong Fan,Yifan Wang,Qi Yan,Ying Ding,Daniel E. Weeks,Zhaohui Lu,Haobo Ren,Richard J. Cook,Momiao Xiong,Anand Swaroop,Emily Y. Chew,Wei Chen +11 more
TL;DR: Cox proportional hazard models using functional regression (FR) to perform gene‐based association analysis of survival traits while adjusting for covariates and likelihood ratio test (LRT) statistics to test for associations between the survival traits and multiple genetic variants in a genetic region are developed.
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Soy Protein Nanofiber Scaffolds for Uniform Maturation of Human Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.
Michael A. Phelan,Michael A. Phelan,Kamil Kruczek,John H Wilson,Matthew Brooks,Charles T. Drinnan,Florian Regent,Jonathan A. Gerstenhaber,Anand Swaroop,Peter I. Lelkes,Tiansen Li +10 more
TL;DR: The hypothesis that plant protein-derived fibrous scaffolds can provide favorable conditions permissive for the maturation of RPE tissue sheets in vitro is tested and suggests that thematuration of cultured iRPE sheets for subsequent clinical applications might benefit from the use of nanofibrous scaffolding generated from natural proteins.
RPGR-ORF15, Which Is Mutated in Retinitis Pigmentosa, Associates with SMC1, SMC3, and Microtubule
Hemant Khanna,Toby W. Hurd,Concepción Lillo,Xinhua Shu,Sunil K. Parapuram,Shirley He,Masayuki Akimoto,Alan F. Wright,Ben Margolis,David S. Williams,Anand Swaroop +10 more
TL;DR: In this paper, structural maintenance of chromosomes (SMC) 1 and SMC3 were found to be associated with the RCC1-like domain of RPGR-ORF15.
Journal ArticleDOI
Protective Gene Expression Changes Elicited by an Inherited Defect in Photoreceptor Structure
Yagya V. Sharma,Radu Cojocaru,Linda M. Ritter,Nidhi Khattree,Matthew Brooks,Matthew Brooks,Alison J. Scott,Anand Swaroop,Anand Swaroop,Andrew F.X. Goldberg +9 more
TL;DR: It is hypothesized that activation of Egr1 and neurotrophic factors may represent a protective immune mechanism which contributes to the characteristically slow retinal degeneration of the rds mouse model.