Anand Swaroop

TL;DR: The results demonstrate, for the first time in a mammalian species, that cone opsins are phosphorylated and that CAR binds toosphorylated cone opsin phosphorylation after light activation.

TL;DR: It is suggested that Baf may contribute to the phenotype of a photoreceptor degenerative disease by modifying the activity of Crx, and may play a role in regulating tissue- or cell type-specific gene expression by interacting with homeodomain transcription factors.

TL;DR: An expanded analysis substantially improves the understanding of the association between the APOE locus and AMD and provides evidence supporting the role of cholesterol modulation, and low‐density cholesterol specifically, in AMD disease etiology.

TL;DR: An integrated analysis of NRL-centered gene regulatory network is reported by coupling chromatin immunoprecipitation followed by high-throughput sequencing (ChIP–Seq) data from Illumina and ABI platforms with global expression profiling and in vivo knockdown studies, finding genes involved in photoreceptor function include binding sites for both NRL and homeodomain protein CRX.

TL;DR: It is suggested that the retinopathy-associated RD3 protein is part of subnuclear protein complexes involved in diverse processes, such as transcription and splicing, at chromosome 1q32 with retinopathies.