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Anand Swaroop
Researcher at National Institutes of Health
Publications - 528
Citations - 53580
Anand Swaroop is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Retinitis pigmentosa & Retinal degeneration. The author has an hindex of 89, co-authored 508 publications receiving 43170 citations. Previous affiliations of Anand Swaroop include Vision-Sciences, Inc. & Yale University.
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Journal ArticleDOI
Mechanisms of aging in senescence-accelerated mice
Todd A. Carter,Jennifer A. Greenhall,Shigeo Yoshida,Sebastian Fuchs,Robert Helton,Anand Swaroop,David J. Lockhart,Carrolee Barlow +7 more
TL;DR: It is shown that combining the study of inbred mouse strains with interesting traits and gene-expression profiling can lead to the discovery of genes important for complex phenotypes, including a mutation in a fibroblast growth factor gene, Fgf1, and a mutations in and ectopic expression of the gene for the chemokine CCL19, which is involved in the inflammatory response.
Journal ArticleDOI
Dietary Nutrient Intake and Progression to Late Age-Related Macular Degeneration in the Age-Related Eye Disease Studies 1 and 2.
Elvira Agrón,Julie A. Mares,Traci E Clemons,Anand Swaroop,Emily Y. Chew,Tiarnan D L Keenan,Areds +6 more
TL;DR: Higher dietary intake of multiple nutrients, including minerals, vitamins, and carotenoids, is associated with decreased risk of progression to late AMD, and these associations are stronger for GA, for which no treatments are available, than for neovascular AMD.
Journal ArticleDOI
Age-related macular degeneration: a high-resolution genome scan for susceptibility loci in a population enriched for late stage disease
Gonçalo R. Abecasis,B.M. Yashar,Y. Zhao,N.M. Ghiavand,Sepideh Zareparsi,E.H. Branham,Adam C. Reddick,Edward H. Trager,Shigeo Yoshida,J. Bahling,E. Filippova,Susan G. Elner,Mark W. Johnson,Andrew K. Vine,Paul A. Sieving,Samuel G. Jacobson,Julia E. Richards,Anand Swaroop +17 more
TL;DR: The results consolidate the chromosomal locations of several AMD susceptibility loci and, together with previous reports, should facilitate the search for disease-associated sequence variants.
Journal ArticleDOI
Retinitis Pigmentosa GTPase Regulator (RPGR) protein isoforms in mammalian retina: insights into X-linked Retinitis Pigmentosa and associated ciliopathies.
Shirley He,Sunil K. Parapuram,Toby W. Hurd,Babak Behnam,Ben Margolis,Anand Swaroop,Hemant Khanna +6 more
TL;DR: It is shown that RPGR isoforms localize to distinct sub-cellular compartments in mammalian photoreceptors and associate with a number of cilia-centrosomal proteins.
Journal ArticleDOI
Loss of lysophosphatidylcholine acyltransferase 1 leads to photoreceptor degeneration in rd11 mice
James S. Friedman,Bo Chang,Daniel S. Krauth,Irma Lopez,Naushin Waseem,R.E. Hurd,Kecia L. Feathers,Kari Branham,Manessa Shaw,George E. Thomas,Matthew Brooks,Chunqiao Liu,Hirva Bakeri,Maria M Campos,Cécilia Maubaret,Andrew R. Webster,Ignacio R. Rodriguez,Debra A. Thompson,Shomi S. Bhattacharya,Robert K. Koenekoop,John R. Heckenlively,Anand Swaroop,Anand Swaroop +22 more
TL;DR: It is shown that the rd11 mouse mutant and its allelic strain, B6-JR2845, exhibit rapid photoreceptor dysfunction, followed by degeneration of both rods and cones, adding another dimension to an essential role for LPCAT1 in retinalPhotoreceptor homeostasis.