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Andrea S. Bauer
Researcher at Boston Children's Hospital
Publications - 137
Citations - 3599
Andrea S. Bauer is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Pancreatic cancer & Medicine. The author has an hindex of 27, co-authored 123 publications receiving 2946 citations. Previous affiliations of Andrea S. Bauer include Harvard University & Stanford University.
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Journal ArticleDOI
Toward the blood-borne miRNome of human diseases
Andreas Keller,Petra Leidinger,Andrea S. Bauer,Abdou ElSharawy,Jan Haas,Christina Backes,Anke Wendschlag,Nathalia Giese,Christine Tjaden,Katja Ott,Jens Werner,Thilo Hackert,Klemens Ruprecht,Hanno Huwer,Junko Huebers,Gunnar Jacobs,Philip Rosenstiel,Henrik Dommisch,Arne S. Schaefer,Joachim Müller-Quernheim,Bernd Wullich,Bastian Keck,Norbert Graf,Joerg Reichrath,Britta Vogel,Almut Nebel,Sven Uwe Jager,Peer F Staehler,Ioannis Amarantos,Valesca Boisguerin,Cord F Staehler,Markus Beier,Matthias Scheffler,Markus W. Büchler,J Wischhusen,Sebastian F M Haeusler,Johannes Dietl,Sylvia Hofmann,Hans-Peter Lenhof,Stefan Schreiber,Hugo A. Katus,Wolfgang Rottbauer,Benjamin Meder,Joerg Hoheisel,Andre Franke,Eckart Meese +45 more
TL;DR: In a multicenter study, the expression profiles of 863 microRNAs were determined by array analysis of 454 blood samples from human individuals with different cancers or noncancer diseases, and this 'miRNome' was validated by quantitative real-time PCR.
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Tumor Recurrence and Survival in Patients Treated for Thymomas and Thymic Squamous Cell Carcinomas: A Retrospective Analysis
Philipp Ströbel,Andrea S. Bauer,Bernhard Puppe,Til Kraushaar,Axel Krein,Klaus V. Toyka,Ralf Gold,Michael Semik,Reinhard Kiefer,Wilfred Nix,Berthold Schalke,Hans Konrad Müller-Hermelink,Alexander Marx +12 more
TL;DR: The long-term outcome of TET patients is related to tumor stage, WHO histotype, completeness of surgical removal, and type of treatment, and Prospective trials are warranted to formally address the efficacy of adjuvant therapy in the treatment of localized and advanced malignant TETs.
Journal ArticleDOI
Alterations in cardiac DNA methylation in human dilated cardiomyopathy
Jan Haas,Karen S. Frese,Yoon Jung Park,Yoon Jung Park,Andreas Keller,Britta Vogel,Anders Lindroth,Dieter Weichenhan,Jennifer Franke,Simon Fischer,Andrea S. Bauer,Sabine Marquart,Farbod Sedaghat-Hamedani,Elham Kayvanpour,Doreen Köhler,Nadine M. Wolf,Sarah Hassel,Rouven Nietsch,Thomas Wieland,Philipp Ehlermann,Jobst Hendrik Schultz,Andreas Dösch,Derliz Mereles,Stefan E. Hardt,Johannes Backs,Jörg D. Hoheisel,Christoph Plass,Christoph Plass,Hugo A. Katus,Benjamin Meder +29 more
TL;DR: DNA methylation differences in pathways related to heart disease, but also in genes with yet unknown function in DCM or heart failure are detected, namely Lymphocyte antigen 75 (LY75), Tyrosine kinase‐type cell surface receptor HER3 (ERBB3), Homeobox B13 (HOXB13) and Adenosine receptor A2A (ADORA2A).
Journal ArticleDOI
Sulfite Reductase Defines a Newly Discovered Bottleneck for Assimilatory Sulfate Reduction and Is Essential for Growth and Development in Arabidopsis thaliana
Muhammad Sayyar Khan,Florian H. Haas,Arman Allboje Samami,Amin Moghaddas Gholami,Andrea S. Bauer,Kurt Fellenberg,Michael Reichelt,Robert Hänsch,Ralf R. Mendel,Andreas J. Meyer,Markus Wirtz,Ruediger Hell +11 more
TL;DR: The results support thatSiR is the only gene with this function in the Arabidopsis genome, that optimal activity of SiR is essential for normal growth, and that its downregulation causes severe adaptive reactions of primary and secondary metabolism.
Journal ArticleDOI
Epigenome-Wide Association Study Identifies Cardiac Gene Patterning and a Novel Class of Biomarkers for Heart Failure.
Benjamin Meder,Jan Haas,Farbod Sedaghat-Hamedani,Elham Kayvanpour,Karen S. Frese,Alan Lai,Rouven Nietsch,Christina Scheiner,Stefan Mester,Diana Martins Bordalo,Ali Amr,Carsten Dietrich,Dietmar Pils,Dominik Siede,Hauke Hund,Andrea S. Bauer,Daniel B. Holzer,Arjang Ruhparwar,Matthias Mueller-Hennessen,Dieter Weichenhan,Christoph Plass,Tanja Weis,Johannes Backs,Maximilian Wuerstle,Andreas Keller,Hugo A. Katus,Andreas E. Posch +26 more
TL;DR: This first epigenome-wide association study in living patients with heart failure using a multi-omics approach links a subset of 517 epigenetic loci with dilated cardiomyopathy and cardiac gene expression and identifies distinct epigenetic methylation patterns that are conserved across tissues.