Federica Armanini

TL;DR: Thousands of microbial genomes from yet-to-be-named species are identified, the pangenomes of human-associated microbes are expanded, and better exploitation of metagenomic technologies are allowed.

TL;DR: The mother-to-infant microbiome transmission routes that are integral in the development of the infant microbiome are described, including maternal gut strains that proved more persistent in the infant gut and ecologically better adapted than those acquired from other sources.

TL;DR: The combined analysis of heterogeneous CRC cohorts identified reproducible microbiome biomarkers and accurate disease-predictive models that can form the basis for clinical prognostic tests and hypothesis-driven mechanistic studies.

TL;DR: This work demonstrated that it is possible to track the vertical transmission of microbial strains from mother to infants and to characterize their transcriptional activity, and provides the foundation for larger-scale surveys to identify the routes of vertical microbial transmission and its influence on postinfancy microbiome development.

TL;DR: Genomic analysis showed substantial functional diversity in the P. copri complex with notable differences in carbohydrate metabolism, suggesting that multi-generational dietary modifications may be driving reduced prevalence in Westernized populations.