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Andy R Ness
Researcher at University Hospitals Bristol NHS Foundation Trust
Publications - 425
Citations - 38919
Andy R Ness is an academic researcher from University Hospitals Bristol NHS Foundation Trust. The author has contributed to research in topics: Body mass index & Population. The author has an hindex of 87, co-authored 415 publications receiving 35275 citations. Previous affiliations of Andy R Ness include National Institute for Health Research & University of Bristol.
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Journal ArticleDOI
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
Timothy M. Frayling,Nicholas J. Timpson,Michael N. Weedon,Eleftheria Zeggini,Eleftheria Zeggini,Eleftheria Zeggini,Rachel M. Freathy,Cecilia M. Lindgren,John R. B. Perry,Katherine S. Elliott,Katherine S. Elliott,Hana Lango,Nigel W. Rayner,Nigel W. Rayner,Nigel W. Rayner,Beverley M. Shields,Lorna W. Harries,Jeffrey C. Barrett,Jeffrey C. Barrett,Sian Ellard,Christopher J. Groves,Christopher J. Groves,Bridget A. Knight,Ann-Marie Patch,Andy R Ness,Shah Ebrahim,Debbie A Lawlor,Susan M. Ring,Yoav Ben-Shlomo,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Ulla Sovio,Ulla Sovio,Amanda J. Bennett,Amanda J. Bennett,David Melzer,Luigi Ferrucci,Ruth J. F. Loos,Inês Barroso,Nicholas J. Wareham,Fredrik Karpe,Fredrik Karpe,Katharine R. Owen,Katharine R. Owen,Lon R. Cardon,Mark Walker,Graham A. Hitman,Graham A. Hitman,Colin N. A. Palmer,Colin N. A. Palmer,Alex S. F. Doney,Alex S. F. Doney,Andrew D. Morris,George Davey Smith,Andrew T. Hattersley,Mark I. McCarthy +55 more
TL;DR: A genome-wide search for type 2 diabetes–susceptibility genes identified a common variant in the FTO (fat mass and obesity associated) gene that predisposes to diabetes through an effect on body mass index (BMI).
Journal ArticleDOI
Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children
Andy Boyd,Jean Golding,John Macleod,Debbie A Lawlor,Abigail Fraser,John Henderson,Lynn Molloy,Andy R Ness,Susan M. Ring,George Davey Smith +9 more
TL;DR: The Avon Longitudinal Study of Parents and Children (ALSPAC) is a transgenerational prospective observational study investigating influences on health and development across the life course and is currently set up as a supported access resource.
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Cohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort
Abigail Fraser,Corrie Macdonald-Wallis,Kate Tilling,Andy Boyd,Jean Golding,George Davey Smith,John Henderson,John Macleod,Lynn Molloy,Andy R Ness,S M Ring,Scott M. Nelson,Debbie A Lawlor +12 more
TL;DR: The Avon Longitudinal Study of Children and Parents (ALSPAC) was established to understand how genetic and environmental characteristics influence health and development in parents and children.
Journal ArticleDOI
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
Cristen J. Willer,Elizabeth K. Speliotes,Elizabeth K. Speliotes,Ruth J. F. Loos,Shengxu Li,Cecilia M. Lindgren,Iris M. Heid,Sonja I. Berndt,Amanda F. Elliott,Amanda F. Elliott,Anne U. Jackson,Claudia Lamina,Guillaume Lettre,Guillaume Lettre,Noha Lim,Helen N. Lyon,Helen N. Lyon,Steven A. McCarroll,Steven A. McCarroll,Konstantinos A. Papadakis,Lu Qi,Joshua C. Randall,Rosa Maria Roccasecca,Serena Sanna,Paul Scheet,Michael N. Weedon,Eleanor Wheeler,Jing Hua Zhao,Leonie C. Jacobs,Inga Prokopenko,Nicole Soranzo,Nicole Soranzo,Toshiko Tanaka,Nicholas J. Timpson,Peter Almgren,Amanda J. Bennett,Richard N. Bergman,Sheila Bingham,Lori L. Bonnycastle,Morris Brown,Noël P. Burtt,Peter S. Chines,Lachlan J. M. Coin,Francis S. Collins,John M. C. Connell,Cyrus Cooper,George Davey Smith,Elaine M. Dennison,Parimal Deodhar,Paul Elliott,Michael R. Erdos,Karol Estrada,David M. Evans,Lauren Gianniny,Christian Gieger,Christopher J. Gillson,Candace Guiducci,Rachel Hackett,David Hadley,Alistair S. Hall,Aki S. Havulinna,Johannes Hebebrand,Albert Hofman,Bo Isomaa,Kevin B. Jacobs,Toby Johnson,Toby Johnson,Pekka Jousilahti,Zorica Jovanovic,Zorica Jovanovic,Kay-Tee Khaw,Peter Kraft,Mikko Kuokkanen,Mikko Kuokkanen,Johanna Kuusisto,Jaana Laitinen,Edward G. Lakatta,Jian'an Luan,Robert Luben,Massimo Mangino,Wendy L. McArdle,Thomas Meitinger,Antonella Mulas,Patricia B. Munroe,Narisu Narisu,Andy R Ness,Kate Northstone,Stephen O'Rahilly,Stephen O'Rahilly,Carolin Purmann,Carolin Purmann,Matthew G. Rees,Martin Ridderstråle,Susan M. Ring,Fernando Rivadeneira,Aimo Ruokonen,Manjinder S. Sandhu,Manjinder S. Sandhu,Jouko Saramies,Laura J. Scott,Angelo Scuteri,Kaisa Silander,Matthew A. Sims,Kijoung Song,Jonathan Stephens,Suzanne Stevens,Heather M. Stringham,Y. C. Loraine Tung,Y. C. Loraine Tung,Timo T. Valle,Cornelia M. van Duijn,Karani Santhanakrishnan Vimaleswaran,Karani Santhanakrishnan Vimaleswaran,Peter Vollenweider,Gérard Waeber,Chris Wallace,Richard M. Watanabe,Dawn M. Waterworth,Nicholas A. Watkins,Jacqueline C. M. Witteman,Eleftheria Zeggini,Guangju Zhai,M. Carola Zillikens,David Altshuler,David Altshuler,Mark J. Caulfield,Stephen J. Chanock,I. Sadaf Farooqi,I. Sadaf Farooqi,Luigi Ferrucci,Jack M. Guralnik,Andrew T. Hattersley,Frank B. Hu,Marjo-Riitta Järvelin,Markku Laakso,Vincent Mooser,Ken K. Ong,Willem H. Ouwehand,Willem H. Ouwehand,Veikko Salomaa,Nilesh J. Samani,Tim D. Spector,Tiinamaija Tuomi,Jaakko Tuomilehto,Manuela Uda,André G. Uitterlinden,Nicholas J. Wareham,Panagiotis Deloukas,Timothy M. Frayling,Leif Groop,Leif Groop,Richard B. Hayes,David J. Hunter,David J. Hunter,Karen L. Mohlke,Leena Peltonen,Leena Peltonen,Leena Peltonen,David Schlessinger,David P. Strachan,H-Erich Wichmann,Mark I. McCarthy,Michael Boehnke,Inês Barroso,Gonçalo R. Abecasis,Joel N. Hirschhorn,Joel N. Hirschhorn +166 more
TL;DR: Several of the likely causal genes are highly expressed or known to act in the central nervous system (CNS), emphasizing, as in rare monogenic forms of obesity, the role of the CNS in predisposition to obesity.
Journal ArticleDOI
Early life risk factors for obesity in childhood: cohort study
John J. Reilly,Julie Armstrong,Ahmad Reza Dorosty,Pauline M Emmett,Andy R Ness,Imogen Rogers,Colin D Steer,Andrea Sherriff +7 more
TL;DR: Eight factors in early life are associated with an increased risk of obesity in childhood, including parental obesity and catch-up growth.