A
Aneesh Chandran
Researcher at Indian Institute of Science
Publications - 21
Citations - 542
Aneesh Chandran is an academic researcher from Indian Institute of Science. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 7, co-authored 15 publications receiving 271 citations. Previous affiliations of Aneesh Chandran include University of Michigan & University of Cambridge.
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Journal ArticleDOI
Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure
Catherine J. Reynolds,Corinna Pade,Joseph Gibbons,Diana Munoz Sandoval,George Joy,Nasim Forooghi,Charlotte Manisty,James C. Moon,Rosemary J. Boyton,Hakam Abbass,Aderonke Abiodun,Mashael Alfarih,Zoe Alldis,Daniel M. Altmann,Oliver E. Amin,Mervyn Andiapen,Jessica Artico,João B Augusto,Georgina L Baca,Sasha N. L. Bailey,Anish N Bhuva,Alex Boulter,Ruth Bowles,Olivia V Bracken,Ben O’Brien,Tim Brooks,Natalie Bullock,David Butler,Gabriella Captur,Olivia Carr,Nicola Champion,Carmen Chan,Aneesh Chandran,Tom Coleman,Jorge Couto de Sousa,Xose Couto-Parada,Eleanor Cross,Teresa Cutino-Moguel,Silvia D'Arcangelo,Rhodri H Davies,Brooke Douglas,Cecilia Di Genova,Keenan Dieobi-Anene,Mariana O. Diniz,Ana Gabriela Aguilar Ellis,Karen Feehan,M. Finlay,Marianna Fontana,Sasha Francis,David Gillespie,Derek W. Gilroy,Matt Hamblin,Gabriella Harker,Georgia C. Hemingway,Jacqueline Hewson,Wendy E. Heywood,Lauren M. Hickling,Bethany Hicks,Aroon D. Hingorani,Lee Howes,Ivie Itua,Victor Jardim,Wing-Yiu Jason Lee,Melanie Jensen,Jessica Jones,Meleri Jones,V. S. Kapil,Caoimhe Kelly,H. Kurdi,Jonathan Lambourne,Kai-Min Lin,Siyi Liu,Aaron Lloyd,Sarah Louth,Mala K. Maini,Vineela Mandadapu,Áine McKnight,Katia Menacho,C. Mfuko,Kevin Mills,Sebastian Millward,Oliver Mitchelmore,Christopher William Moon,Sam M. Murray,Mahdad Noursadeghi,Ashley Otter,Susana Palma,Ruth Parker,Kush Patel,Mihaela Pawarova,Steffen E. Petersen,Brian Piniera,Franziska P Pieper,Lisa Rannigan,Alicja Rapala,Amy Richards,Matthew Robathan,Joshua Rosenheim,Cathy Rowe,M Royds,Jane Sackville West,Genine Sambile,Nathalie Schmidt,Hannah Selman,Amanda Semper,Andreas Seraphim,Mihaela Simion,Angelique Smit,Michelle Sugimoto,Leo Swadling,Stephen Taylor,Nigel J. Temperton,Stephen Thomas,George Douglas Thornton,Thomas A. Treibel,Arthur Tucker,A. Varghese,Jessry Veerapen,Mohit Vijayakumar,Time Warner,Sophie Welch,Hannah White,Theresa Wodehouse,Lucinda Wynne,Dan Zahedi,Benjamin M. Chain +125 more
TL;DR: B and T cell immunity against previous variants of concern was enhanced in triple vaccinated individuals, but magnitude of T and B cell responses against B.1.1 .1.529 spike protein was reduced.
Journal ArticleDOI
Groove binding mechanism of ionic liquids: a key factor in long-term stability of DNA in hydrated ionic liquids?
TL;DR: Simulation and experimental results show that DNA maintains the native B-conformation in ILs, and suggest that partial dehydration by ILs likely prevents the hydrolytic reactions that denature DNA and helps stabilize DNA for the long term.
Journal ArticleDOI
Self-Assembled Inverted Micelles Stabilize Ionic Liquid Domains in Supercritical CO2
TL;DR: The study reveals direct evidence of the existence of stable IL droplets within a continuous CO(2) phase through amphiphilic surfactants and reveals that the stability of the microemulsions mainly pertains to the IL anion-headgroup interactions, while the cations play a secondary role.
Journal ArticleDOI
Targeting the pregnane X receptor using microbial metabolite mimicry
Zdeněk Dvořák,Felix Kopp,Cait M. Costello,Jazmin S. Kemp,Hao Li,Aneta Vrzalová,Martina Stepankova,Iveta Iveta Bartonkov,Eva Jiskrová,Karolína Poulíková,Barbora Vyhlídalová,Lars U. Nordstroem,Chamini V. Karunaratne,Harmit S. Ranhotra,Kyu Shik Mun,Anjaparavanda P. Naren,Iain A. Murray,Gary H. Perdew,Julius Brtko,Lucia Toporova,Arne Schön,Bret D. Wallace,William G. Walton,Matthew R. Redinbo,Katherine Sun,Amanda P. Beck,Sandhya Kortagere,Michelle C. Neary,Aneesh Chandran,Saraswathi Vishveshwara,Maria Maddalena Cavalluzzi,Giovanni Lentini,Julia Yue Cui,Haiwei Gu,John C. March,Shirshendu Chatterjee,Adam P. Matson,Dennis L. Wright,Kyle L. Flannigan,Simon A. Hirota,Ryan Balfour Sartor,Sridhar Mani +41 more
TL;DR: FKK6 significantly represses pro‐inflammatory cytokine production cells and abrogates inflammation in mice expressing the human PXR gene, demonstrating for the first time that microbial metabolite mimicry is a viable strategy for drug discovery and opens the door to underexploited regions of chemical space.
Journal ArticleDOI
Structure and dynamics of acetate anion-based ionic liquids from molecular dynamics study
TL;DR: In this article, molecular dynamics simulation results of three acetate anion-based ionic liquids that encompass the most common IL cations are reported, based on a set of proposed force field parameters.