S
Sophie Welch
Researcher at St Bartholomew's Hospital
Publications - 5
Citations - 260
Sophie Welch is an academic researcher from St Bartholomew's Hospital. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 2 publications receiving 19 citations.
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Journal ArticleDOI
Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure
Catherine J. Reynolds,Corinna Pade,Joseph Gibbons,Diana Munoz Sandoval,George Joy,Nasim Forooghi,Charlotte Manisty,James C. Moon,Rosemary J. Boyton,Hakam Abbass,Aderonke Abiodun,Mashael Alfarih,Zoe Alldis,Daniel M. Altmann,Oliver E. Amin,Mervyn Andiapen,Jessica Artico,João B Augusto,Georgina L Baca,Sasha N. L. Bailey,Anish N Bhuva,Alex Boulter,Ruth Bowles,Olivia V Bracken,Ben O’Brien,Tim Brooks,Natalie Bullock,David Butler,Gabriella Captur,Olivia Carr,Nicola Champion,Carmen Chan,Aneesh Chandran,Tom Coleman,Jorge Couto de Sousa,Xose Couto-Parada,Eleanor Cross,Teresa Cutino-Moguel,Silvia D'Arcangelo,Rhodri H Davies,Brooke Douglas,Cecilia Di Genova,Keenan Dieobi-Anene,Mariana O. Diniz,Ana Gabriela Aguilar Ellis,Karen Feehan,M. Finlay,Marianna Fontana,Sasha Francis,David Gillespie,Derek W. Gilroy,Matt Hamblin,Gabriella Harker,Georgia C. Hemingway,Jacqueline Hewson,Wendy E. Heywood,Lauren M. Hickling,Bethany Hicks,Aroon D. Hingorani,Lee Howes,Ivie Itua,Victor Jardim,Wing-Yiu Jason Lee,Melanie Jensen,Jessica Jones,Meleri Jones,V. S. Kapil,Caoimhe Kelly,H. Kurdi,Jonathan Lambourne,Kai-Min Lin,Siyi Liu,Aaron Lloyd,Sarah Louth,Mala K. Maini,Vineela Mandadapu,Áine McKnight,Katia Menacho,C. Mfuko,Kevin Mills,Sebastian Millward,Oliver Mitchelmore,Christopher William Moon,Sam M. Murray,Mahdad Noursadeghi,Ashley Otter,Susana Palma,Ruth Parker,Kush Patel,Mihaela Pawarova,Steffen E. Petersen,Brian Piniera,Franziska P Pieper,Lisa Rannigan,Alicja Rapala,Amy Richards,Matthew Robathan,Joshua Rosenheim,Cathy Rowe,M Royds,Jane Sackville West,Genine Sambile,Nathalie Schmidt,Hannah Selman,Amanda Semper,Andreas Seraphim,Mihaela Simion,Angelique Smit,Michelle Sugimoto,Leo Swadling,Stephen Taylor,Nigel J. Temperton,Stephen Thomas,George Douglas Thornton,Thomas A. Treibel,Arthur Tucker,A. Varghese,Jessry Veerapen,Mohit Vijayakumar,Time Warner,Sophie Welch,Hannah White,Theresa Wodehouse,Lucinda Wynne,Dan Zahedi,Benjamin M. Chain +125 more
TL;DR: B and T cell immunity against previous variants of concern was enhanced in triple vaccinated individuals, but magnitude of T and B cell responses against B.1.1 .1.529 spike protein was reduced.
Journal ArticleDOI
Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy study.
Rishi K Gupta,Joshua Rosenheim,Lucy C K Bell,Aneesh Chandran,José Afonso Guerra-Assunção,Gabriele Pollara,Matthew Whelan,Jessica Artico,George Joy,Hibba Kurdi,Daniel M. Altmann,Rosemary J. Boyton,Mala K. Maini,Áine McKnight,Jonathan Lambourne,Teresa Cutino-Moguel,Charlotte Manisty,Charlotte Manisty,Thomas A. Treibel,Thomas A. Treibel,James C. Moon,James C. Moon,Benjamin M. Chain,Mahdad Noursadeghi,Hakam Abbass,Aderonke Abiodun,Mashael Alfarih,Zoe Alldis,Oliver E. Amin,Mervyn Andiapen,João B Augusto,Georgiana L Baca,Sasha N. L. Bailey,Anish N Bhuva,Alex Boulter,Ruth Bowles,Olivia V Bracken,Ben O’Brien,Tim Brooks,Natalie Bullock,David Butler,Gabriella Captur,Nicola Champion,Carmen Chan,David Collier,Jorge Couto de Sousa,Xose Couto-Parada,Rhodri H Davies,Brooke Douglas,Cecilia Di Genova,Keenan Dieobi-Anene,Mariana O. Diniz,Anaya Ellis,Karen Feehan,Malcolm Finlay,Marianna Fontana,Nasim Forooghi,Celia Gaier,Joseph M Gibbons,Derek W. Gilroy,Matt Hamblin,Gabrielle Harker,Jacqueline Hewson,Lauren M Hickling,Aroon D. Hingorani,Lee Howes,Alun D. Hughes,Gemma Hughes,Rebecca Hughes,Ivie Itua,Victor Jardim,Wing-Yiu Jason Lee,Melaniepetra Jensen,Jessica Jones,Meleri Jones,Vikas Kapil,Kai-Min Lin,Sarah Louth,Vineela Mandadapu,Katia Menacho,Celina Mfuko,Oliver Mitchelmore,Christopher William Moon,Diana Munoz Sandoval,Sam M. Murray,Ashley Otter,Corinna Pade,Susana Palma,Ruth M. Parker,Kush Patel,Babita Pawarova,Steffen E. Petersen,Brian Piniera,Franziska P Pieper,Daniel Pope,Maria Prossora,Lisa Rannigan,Alicja Rapala,Catherine J. Reynolds,Amy Richards,Matthew Robathan,Genine Sambile,Nathalie M. Schmidt,Amanda Semper,Andreas Seraphim,Mihaela Simion,Angelique Smit,Michelle Sugimoto,Leo Swadling,Stephen Taylor,Nigel J. Temperton,Stephen B. Thomas,George Thornton,Art Tucker,Jessry Veerapen,Mohit Vijayakumar,Sophie Welch,Theresa Wodehouse,Lucinda Wynne,Dan Zahedi +119 more
TL;DR: In this paper, a nested case-control diagnostic accuracy study among a prospective cohort of health-care workers undergoing weekly blood and nasopharyngeal swab sampling for whole-blood RNA sequencing and SARS-CoV-2 PCR testing, when fit to attend work, was conducted.
Journal ArticleDOI
Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19
João B Augusto,João B Augusto,Katia Menacho,Katia Menacho,Mervyn Andiapen,Mervyn Andiapen,Ruth Bowles,Ruth Bowles,Maudrian Burton,Maudrian Burton,Sophie Welch,Anish N Bhuva,Anish N Bhuva,Andreas Seraphim,Andreas Seraphim,Corinna Pade,George Joy,George Joy,Melanie Jensen,Rhodri H Davies,Rhodri H Davies,Gabriella Captur,Gabriella Captur,Marianna Fontana,Marianna Fontana,Hugh Montgomery,Ben O’Brien,Ben O’Brien,Aroon D. Hingorani,Teresa Cutino-Moguel,Áine McKnight,Hakam Abbass,Mashael Alfarih,Mashael Alfarih,Zoe Alldis,Georgina L Baca,Alex Boulter,Olivia V Bracken,Natalie Bullock,Nicola Champion,Carmen Chan,Xose Couto-Parada,Keenan Dieobi-Anene,Karen Feehan,Gemma A. Figtree,Melanie Figtree,Malcolm Finlay,Nasim Forooghi,Joseph M Gibbons,Peter Griffiths,Matt Hamblin,Lee Howes,Ivie Itua,Meleri Jones,Victor Jardim,Vikas Kapil,Vikas Kapil,Wing-Yiu Jason Lee,Vineela Mandadapu,Celina Mfuko,Oliver Mitchelmore,Susana Palma,Kush Patel,Kush Patel,Steffen E. Petersen,Steffen E. Petersen,Brian Piniera,Rosalind Raine,Alicja Rapala,Amy Richards,Genine Sambile,Jorge Couto de Sousa,Michelle Sugimoto,George Thornton,George Thornton,Jessica Artico,Dan Zahedi,Ruth M. Parker,Mathew Robathan,Lauren M Hickling,Ntobeko A B Ntusi,Amanda Semper,Tim Brooks,Jessica Jones,Art Tucker,Art Tucker,Jessry Veerapen,Mohit Vijayakumar,Theresa Wodehouse,Lucinda Wynne,Thomas A. Treibel,Thomas A. Treibel,Mahdad Noursadeghi,Charlotte Manisty,Charlotte Manisty,James C. Moon,James C. Moon +96 more
TL;DR: This COVID-19 bioresource established just before the peak of infections in the UK will provide longitudinal assessments of incident infection and immune responses in HCWs through the natural time course of disease and convalescence.
Journal ArticleDOI
Non-invasive Electrocardiographic Imaging guided targeting of drivers of persistent atrial fibrillation: the TARGET-AF1 trial.
Shohreh Honarbakhsh,Gurpreet Dhillon,H. Abbas,Peter Henry Waddingham,Adam Sc Dennis,N Ahluwalia,Sophie Welch,H Daw,Simon Sporton,Anthony Chow A,Mark J. Earley,Pier D. Lambiase,Ross J. Hunter +12 more
TL;DR: In this article , the authors used electrocardiographic imaging (ECGI) mapping to guide localized driver ablation in patients with persistent atrial fibrillation (AF) <2 years.
Journal ArticleDOI
Driver characteristics associated with structurally and electrically remodeled atria in persistent atrial fibrillation
Gurpreet Dhillon,Shohreh Honarbakhsh,Adam J. Graham,N Ahluwalia,H. Abbas,Sophie Welch,H Daw,Anthony W.C. Chow,Mark J. Earley,Rui Providência,C. J. Schilling,Pier D. Lambiase,Ross J. Hunter +12 more
TL;DR: In this article , the authors evaluated how left atrial (LA) dilation and time in AF impact persistent atrial fibrillation (AF) mechanisms and demonstrated different AF mechanisms in patient subgroups.