M
Meleri Jones
Researcher at Queen Mary University of London
Publications - 35
Citations - 1898
Meleri Jones is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Virus & Hepatitis C virus. The author has an hindex of 14, co-authored 33 publications receiving 1345 citations. Previous affiliations of Meleri Jones include University College London.
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Journal ArticleDOI
Temporal analysis of early immune responses in patients with acute hepatitis B virus infection.
Claire Dunn,Dimitra Peppa,Pooja Khanna,G. Nebbia,Meleri Jones,Nathan J Brendish,Rm Monica Lascar,David Brown,Rj Gilson,Rj Tedder,Gm Dusheiko,Michael Jacobs,Paul Klenerman,Mk Maini +13 more
TL;DR: The early stages of acute HBV are characterized by induction of interleukin-10 rather than type I IFN, accompanied by a temporary attenuation of NK and T-cell responses, which are correlated with temporal changes in viral load, serology, and liver inflammation.
Journal ArticleDOI
Dengue Virus Inhibits Alpha Interferon Signaling by Reducing STAT2 Expression
Meleri Jones,Andrew D. Davidson,Linda Hibbert,Petra Gruenwald,Joerg F. Schlaak,Simon Ball,Graham R. Foster,Michael Jacobs +7 more
TL;DR: It is shown that in replicon-containing cells dengue virus RNA replication and the replication of encephalomyocarditis virus, an IFN-sensitive virus, are resistant to the antiviral effects ofIFN-α.
Journal ArticleDOI
Dengue Virus NS5 Inhibits Interferon-α Signaling by Blocking Signal Transducer and Activator of Transcription 2 Phosphorylation
TL;DR: DENV NS5 is a potent and specific type I IFN antagonist, which binds signal transducer and activator of transcription 2 and inhibits its phosphorylation.
Journal ArticleDOI
Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure
Catherine J. Reynolds,Corinna Pade,Joseph Gibbons,Diana Munoz Sandoval,George Joy,Nasim Forooghi,Charlotte Manisty,James C. Moon,Rosemary J. Boyton,Hakam Abbass,Aderonke Abiodun,Mashael Alfarih,Zoe Alldis,Daniel M. Altmann,Oliver E. Amin,Mervyn Andiapen,Jessica Artico,João B Augusto,Georgina L Baca,Sasha N. L. Bailey,Anish N Bhuva,Alex Boulter,Ruth Bowles,Olivia V Bracken,Ben O’Brien,Tim Brooks,Natalie Bullock,David Butler,Gabriella Captur,Olivia Carr,Nicola Champion,Carmen Chan,Aneesh Chandran,Tom Coleman,Jorge Couto de Sousa,Xose Couto-Parada,Eleanor Cross,Teresa Cutino-Moguel,Silvia D'Arcangelo,Rhodri H Davies,Brooke Douglas,Cecilia Di Genova,Keenan Dieobi-Anene,Mariana O. Diniz,Ana Gabriela Aguilar Ellis,Karen Feehan,M. Finlay,Marianna Fontana,Sasha Francis,David Gillespie,Derek W. Gilroy,Matt Hamblin,Gabriella Harker,Georgia C. Hemingway,Jacqueline Hewson,Wendy E. Heywood,Lauren M. Hickling,Bethany Hicks,Aroon D. Hingorani,Lee Howes,Ivie Itua,Victor Jardim,Wing-Yiu Jason Lee,Melanie Jensen,Jessica Jones,Meleri Jones,V. S. Kapil,Caoimhe Kelly,H. Kurdi,Jonathan Lambourne,Kai-Min Lin,Siyi Liu,Aaron Lloyd,Sarah Louth,Mala K. Maini,Vineela Mandadapu,Áine McKnight,Katia Menacho,C. Mfuko,Kevin Mills,Sebastian Millward,Oliver Mitchelmore,Christopher William Moon,Sam M. Murray,Mahdad Noursadeghi,Ashley Otter,Susana Palma,Ruth Parker,Kush Patel,Mihaela Pawarova,Steffen E. Petersen,Brian Piniera,Franziska P Pieper,Lisa Rannigan,Alicja Rapala,Amy Richards,Matthew Robathan,Joshua Rosenheim,Cathy Rowe,M Royds,Jane Sackville West,Genine Sambile,Nathalie Schmidt,Hannah Selman,Amanda Semper,Andreas Seraphim,Mihaela Simion,Angelique Smit,Michelle Sugimoto,Leo Swadling,Stephen Taylor,Nigel J. Temperton,Stephen Thomas,George Douglas Thornton,Thomas A. Treibel,Arthur Tucker,A. Varghese,Jessry Veerapen,Mohit Vijayakumar,Time Warner,Sophie Welch,Hannah White,Theresa Wodehouse,Lucinda Wynne,Dan Zahedi,Benjamin M. Chain +125 more
TL;DR: B and T cell immunity against previous variants of concern was enhanced in triple vaccinated individuals, but magnitude of T and B cell responses against B.1.1 .1.529 spike protein was reduced.
Journal ArticleDOI
Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection.
Catherine J. Reynolds,Leo Swadling,Joseph M Gibbons,Corinna Pade,Melanie Jensen,Mariana O. Diniz,Nathalie M. Schmidt,David Butler,Oliver E. Amin,Sasha N. L. Bailey,Sam M. Murray,Franziska P Pieper,Stephen Taylor,Jessica Jones,Meleri Jones,Wing-Yiu Jason Lee,Joshua Rosenheim,Aneesh Chandran,George Joy,Cecilia Di Genova,Nigel J. Temperton,Jonathan Lambourne,Teresa Cutino-Moguel,Mervyn Andiapen,Marianna Fontana,Angelique Smit,Amanda Semper,Ben O’Brien,Ben O’Brien,Ben O’Brien,Benjamin M. Chain,Tim Brooks,Charlotte Manisty,Charlotte Manisty,Thomas A. Treibel,Thomas A. Treibel,James C. Moon,James C. Moon,COVIDsortium Investigators,Mahdad Noursadeghi,Daniel M. Altmann,Mala K. Maini,Áine McKnight,Rosemary J. Boyton +43 more
TL;DR: In this paper, the authors analyzed T cell and neutralizing antibody responses in 136 healthcare workers (HCW) 16-18 weeks after United Kingdom lockdown, 76 of whom had mild/asymptomatic SARS-CoV-2 infection captured by serial sampling.