Ann M. Graybiel

TL;DR: Quantitative analysis of neuromelanin-pigmented neurons in control and parkinsonian midbrains demonstrates that the dopamine-containing cell groups of the normal human midbrain differ markedly from each other in the percentage of neurmelan in-pIGmented neurons they contain, and suggests a selective vulnerability of the neuromelsin- pigmented subpopulation of dopamine- containing mesencephalic neurons in Parkinson's disease.

TL;DR: Knowlton BJ, Mangels JA, Squire LR, and Graybiel AM as discussed by the authors showed that activation of a basal ganglia-forebrain circuit prevents plasticity of learned vocalizations.

TL;DR: It is proposed that differential activation of immediate-early genes by psychostimulants may be an early step in drug-specific molecular cascades contributing to acute and long-lasting psychostIMulant-induced changes in behavior.

TL;DR: It is proposed that one aspect of basal ganglia-based learning is the recoding of cortically derived information within the striatum that can chunk the representations of motor and cognitive action sequences so that they can be implemented as performance units.

TL;DR: Large and widely distributed changes in the neuronal activity patterns occurred in the sensorimotor striatum during behavioral acquisition, culminating in task-related activity emphasizing the beginning and end of the automatized procedure.