Ann M. Graybiel

TL;DR: This immediate toggling between breaking old habits and returning to them demonstrates that even semiautomatic behaviors are under cortical control and that this control occurs online, second by second.

TL;DR: The distribution of D1 dopamine receptors was studied autoradiographically in the basal ganglia of the cat, monkey and human to conclude that D1 binding is compartmentalized in the dorsal striatum and that this is likely to be of functional significance in the dopaminergic modulation of intrastriatal neurotransmission as well as of afferent and efferent neurotransmission.

TL;DR: Injections of the retrograde tracer, wheat germ agglutinated-horseradish peroxidase were placed in the substantia nigra, in adjoining dopamine-containing cell groups A8 and A10, and in the internal and external parts of the pallidal complex of 20 cats in order to identify the compartmental origins of striatal efferent projections to the pallidum and midbrain.

TL;DR: Results establish that differential patterns of expression of fos/jun genes occur in striatal neurons following exposure to cocaine, a potent psychomotor stimulant, and suggest that these tissue-specific patterns of gene expression may contribute to the response specificity of Striatal neurons to stimulation by monoamines including dopamine.

TL;DR: Two new LAD cases are reported in which lymphocytes, neutrophils, and platelets share severe defects in β1, β2, and β3 integrin activation, and CalDAG-GEFI is identified as a critical regulator of inside-out integrinactivation in human T lymphocytes.