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Ann M. Graybiel
Researcher at McGovern Institute for Brain Research
Publications - 360
Citations - 53036
Ann M. Graybiel is an academic researcher from McGovern Institute for Brain Research. The author has contributed to research in topics: Striatum & Basal ganglia. The author has an hindex of 121, co-authored 350 publications receiving 49771 citations. Previous affiliations of Ann M. Graybiel include Case Western Reserve University & Tufts University.
Papers
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Journal ArticleDOI
Simultaneous recording and marking of brain microstructures.
Khalil B. Ramadi,Canan Dagdeviren,Preksha Bhagchandani,Carlos Nunez-Lopez,Carlos Nunez-Lopez,Min Jung Kim,Robert Langer,Ann M. Graybiel,Michael J. Cima +8 more
TL;DR: A customizable concentric marking electrode (CME) consisting of an iron core within a 125 μm-stainless steel (SS) sheath for co-localization of targeted regions in the brain and it is demonstrated that iron microdeposits are remarkably stable and persist up to 10 months post-deposition.
Patent
Systems and methods for delivering chemical and electrical stimulation across one or more neural circuits
TL;DR: In this paper, a system for delivering chemical and electrical stimulation across one or more neural circuits is described, where a distal tip of the delivery tube is configured to be positionable adjacent to the one or multiple neural circuits.
Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c
Yi-Chuan Chen,Hsiao-Ying Kuo,Ulrich Bornschein,Hiroshi Takahashi,Shih-Yun Chen,Kuan-Ming Lu,Hao-Yu Yang,Gui-May Chen,Jing-Ruei Lin,Yi Hsin Lee,Yun-Chia Chou,Sin-Jhong Cheng,Cheng-Ting Chien,Wolfgang Enard,Wulf Hevers,Svante Pääbo,Fu Chin Liu,Ann M. Graybiel +17 more
TL;DR: In this paper, the mouse striatum was shown to negatively interact with the synapse suppressor gene Mef2c, which can itself be repressed by Foxp2 through direct DNA binding.
Journal ArticleDOI
Striosomes and Matrisomes: Scaffolds for Dynamic Coupling of Volition and Action.
Ann M. Graybiel,Ayano Matsushima +1 more
TL;DR: Striosomes form neurochemically specialized compartments of the striatum embedded in a large matrix made up of modules called matrisomes and are spatially interspersed among interneurons and are influenced by local and global neuromodulatory and oscillatory activities as discussed by the authors .
Book ChapterDOI
Protein Phosphatases Regulate Creb Phosphorylation and Fos Expression in the Developing Striatum
Fu Chin Liu,Ann M. Graybiel +1 more
TL;DR: Dopamine is a classical neurotransmitter of multiple functions that not only can modulate short-term synaptic activity, but also can regulate long-term changes in gene expression.