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Ann M. Graybiel
Researcher at McGovern Institute for Brain Research
Publications - 360
Citations - 53036
Ann M. Graybiel is an academic researcher from McGovern Institute for Brain Research. The author has contributed to research in topics: Striatum & Basal ganglia. The author has an hindex of 121, co-authored 350 publications receiving 49771 citations. Previous affiliations of Ann M. Graybiel include Case Western Reserve University & Tufts University.
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Compartmental origins of the striatopallidal projection in the primate.
TL;DR: It is concluded that in the primate, separate lines of conduction lead from the striatum to the external and the internal pallidal segments, and raise the possibility that the cells of origin of these pathways form a mosaic in the extrastriosomal matrix.
Journal Article
The nigrostriatal system in Parkinson's disease.
TL;DR: In this paper, the effects of dopaminergic cell loss and mesostriatal fiber loss in the caudate nucleus and putamen for cases of idiopathic Parkinson's disease were investigated.
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Characterization of Mechanically Matched Hydrogel Coatings to Improve the Biocompatibility of Neural Implants
Kevin C. Spencer,Jay C. Sy,Jay C. Sy,Khalil B. Ramadi,Ann M. Graybiel,Robert Langer,Michael J. Cima +6 more
TL;DR: The ability of soft hydrogel coatings to modulate glial scar formation by reducing local strain is explored and increasing implant diameter was found to significantly increase scarring for glass implants, as well as increase local BBB permeability, increase macrophage activation, and decrease the local neural density.
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Neuroleptic-sensitive binding sites in the nigrostriatal system: evidence for differential distribution of sigma sites in the substantia nigra, pars compacta of the cat.
TL;DR: Evidence suggests that sigma-mediated interactions with dopaminergic systems may occur in the substantia nigra pars compacta and that the functional effects of these interactions may influence the nigrostriatal projection to striosomes differentially.
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Optogenetics: 10 years after ChR2 in neurons--views from the community.
Antoine Roger Adamantidis,Antoine Roger Adamantidis,Silvia Arber,Silvia Arber,Jaideep S. Bains,Ernst Bamberg,Antonello Bonci,Antonello Bonci,György Buzsáki,Jessica A. Cardin,Rui M. Costa,Yang Dan,Yang Dan,Yukiko Goda,Ann M. Graybiel,Michael Häusser,Peter Hegemann,John R. Huguenard,Thomas R. Insel,Patricia H. Janak,Daniel Johnston,Sheena A. Josselyn,Christof Koch,Anatol C. Kreitzer,Anatol C. Kreitzer,Christian Lüscher,Robert C. Malenka,Gero Miesenböck,Georg Nagel,Botond Roska,Botond Roska,Mark J. Schnitzer,Mark J. Schnitzer,Krishna V. Shenoy,Krishna V. Shenoy,Ivan Soltesz,Scott M. Sternson,Richard W. Tsien,Roger Y. Tsien,Gina G. Turrigiano,Kay M. Tye,Rachel Wilson +41 more
TL;DR: On the anniversary of the Boyden et al. (2005) paper that introduced the use of channelrhodopsin in neurons, Nature Neuroscience asks selected members of the community to comment on the utility, impact and future of this important technique.