Ann M. Graybiel

TL;DR: The distribution of muscarinic cholinergic binding sites in the striatum was studied in relation to the locations of other neurochemical markers in the developing rat, cat, ferret, and human.

TL;DR: Evidence is presented here that enzyme-positive clumps in the deep collicular layers of the superior colliculus are also seen in the monkey and that, in the cat at least, these clumps do indeed form longitudinal bands.

TL;DR: The effects of the weaver gene discriminate among mesostriatal subsystems not only according to the regional affiliations of these subsystems within the dorsal and ventral striatum, but also according toThe preferential association of the subsystems for the striosomal and matrical compartments of the caudoputamen.

TL;DR: It is suggested that the differential striosome-matrix pattern of dopamine loss could be a key to identifying the mechanisms underlying the genesis of dystonia in DRD.

TL;DR: It is reported here that desipramine-sensitive [3H]mazindol binding sites have highly heterogeneous distributions in the dorsal and the ventral striatum, and the possibility that these distributions could result in selective neuronal vulnerability to neurotoxins, such as 1-methyl-4-phenylpyridine (MPP+), that depend on the dopamine-uptake complex for entry into neurons.