A
Anne Burgevin
Researcher at French Institute of Health and Medical Research
Publications - 12
Citations - 490
Anne Burgevin is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Epitope & MHC class I. The author has an hindex of 8, co-authored 10 publications receiving 458 citations. Previous affiliations of Anne Burgevin include Paris Descartes University & Centre national de la recherche scientifique.
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Journal ArticleDOI
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Stefan Tenzer,E Wee,Anne Burgevin,Anne Burgevin,Guillaume Stewart-Jones,L Friis,Kasper Lamberth,Chang C-H.,Mikkel Harndahl,Mirjana Weimershaus,Mirjana Weimershaus,Jan Gerstoft,Nadja Akkad,Paul Klenerman,Lars Fugger,E Y Jones,Andrew J. McMichael,Søren Buus,Hansjörg Schild,P van Endert,Iversen Akn. +20 more
TL;DR: It is shown that CTL immunodominance in regions of the human immunodeficiency virus type 1 group-associated antigen proteins p17 and p24 correlated with epitope abundance, which was strongly influenced by proteasomal digestion profiles, affinity for the transporter protein TAP, and trimming mediated by the endoplasmatic reticulum aminopeptidase ERAAP.
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Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone
Francesca Fallarino,Giovanni Luca,Mario Calvitti,Francesca Mancuso,Claudio Nastruzzi,Maria C. Fioretti,Ursula Grohmann,Ennio Becchetti,Anne Burgevin,Roland Kratzer,Roland Kratzer,Peter van Endert,Peter van Endert,Louis Boon,Paolo Puccetti,Riccardo Calafiore +15 more
TL;DR: It is reported that isolated neonatal porcine SC, administered alone in highly biocompatible microcapsules, led to diabetes prevention and reversion in the respective 88 and 81% of overtly diabetic (nonobese diabetic [NOD]) mice, with no need for additional β cell or insulin therapy.
Journal ArticleDOI
Compartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action
Avital Lev,Michael F. Princiotta,Damian Zanker,Kazuyo Takeda,James Gibbs,Chiharu Kumagai,Elizabeth Waffarn,Brian P. Dolan,Anne Burgevin,Peter van Endert,Weisan Chen,Jack R. Bennink,Jonathan W. Yewdell +12 more
TL;DR: MHC class I molecules function to display peptides generated from cellular and pathogen gene products for immune surveillance by CD8+ T cells, and compartmentalization of DRiP peptide generation to prevent competition from abundant cytosolic peptides is shown.
Journal ArticleDOI
A detailed analysis of the murine TAP transporter substrate specificity.
Anne Burgevin,Anne Burgevin,Loredana Saveanu,Loredana Saveanu,Yohan Kim,Émilie Barilleau,Émilie Barilleau,Maya F. Kotturi,Alessandro Sette,Peter van Endert,Peter van Endert,Bjoern Peters +11 more
TL;DR: A quantitative model of binding specificity of murine TAP developed herein should be useful for interpreting epitope mapping and immunogenicity data obtained in humanized mouse models.
Journal ArticleDOI
Lysyl tRNA synthetase is required for the translocation of calreticulin to the cell surface in immunogenic death.
Oliver Kepp,Oliver Kepp,Abdelaziz Gdoura,Abdelaziz Gdoura,Isabelle Martins,Isabelle Martins,Theocharis Panaretakis,Frédéric Schlemmer,Frédéric Schlemmer,Antoine Tesniere,Antoine Tesniere,Gian Maria Fimia,Fabiola Ciccosanti,Anne Burgevin,Anne Burgevin,Mauro Piacentini,Paul Eggleton,Philip J. Young,Laurence Zitvogel,Peter van Endert,Peter van Endert,Guido Kroemer,Guido Kroemer +22 more
TL;DR: The contribution of KARS to the emission of (one of) the principal signal(s) of immunogenic cell death, CRT exposure is underscore.