Anshul Kundaje

TL;DR: An updated map of the Drosophila melanogaster regulatory genome based on the location of 84 TRFs at various stages of development reveals a variety of genomic targeting patterns, including factors with strong preferences toward proximal promoter binding, factors that target intergenic and intronic DNA, and factors with distinct chromatin state preferences.

TL;DR: Kipoi, a collaborative initiative to define standards and to foster reuse of trained models in genomics, is presented, providing a unified framework to archive, share, access, use, and build on models developed by the community.

TL;DR: WILDS as mentioned in this paper is a curated collection of 8 benchmark datasets that reflect a diverse range of distribution shifts which naturally arise in real-world applications, such as shifts across hospitals for tumor identification; across camera traps for wildlife monitoring; and across time and location in satellite imaging and poverty mapping.

TL;DR: Nine peak-calling algorithms for predicting enhancers validated by transgenic mouse assays are compared and a superior method for predicting tissue-specific mouse developmental enhancers by reranking the called peaks is devised.

TL;DR: In this paper , a single-nucleus assay for transposase-accessible chromatin with sequencing was applied to profile 28,316 nuclei across coronary artery segments from 41 patients with varying stages of CAD, which revealed 14 distinct cellular clusters.