A
Arimichi Takabayashi
Researcher at Kyoto University
Publications - 64
Citations - 4097
Arimichi Takabayashi is an academic researcher from Kyoto University. The author has contributed to research in topics: Cancer & Immune system. The author has an hindex of 25, co-authored 64 publications receiving 3892 citations. Previous affiliations of Arimichi Takabayashi include University of Helsinki & Ehime University.
Papers
More filters
Journal ArticleDOI
Familial gastrointestinal stromal tumours with germline mutation of the kit gene
Toshirou Nishida,Seiichi Hirota,Masahiko Taniguchi,Koji Hashimoto,Koji Isozaki,Harumi Nakamura,Yuzuru Kanakura,Tomoyuki Tanaka,Arimichi Takabayashi,Hikaru Matsuda,Yukihiko Kitamura +10 more
TL;DR: Familial gastrointestinal stromal tumours with germline mutation of the KIT gene is reported: affected members all have a KIT mutation occurring between the transmembrane and tyrosine kinase domains, which is also the region where mutations have been found in solitary GISTs
Journal ArticleDOI
CD4+CD25+ regulatory T cells in patients with gastrointestinal malignancies: possible involvement of regulatory T cells in disease progression.
TL;DR: The purpose of the current study was to demonstrate the possible involvement of CD4+CD25+ regulatory T cells in immune system impairment in patients with gastrointestinal malignancies.
Journal ArticleDOI
SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion
Takanori Kitamura,Kohei Kometani,Hiroki Hashida,Akihiro Matsunaga,Hiroyuki Miyoshi,Hisahiro Hosogi,Masahiro Aoki,Masanobu Oshima,Masanobu Oshima,Masakazu Hattori,Arimichi Takabayashi,Nagahiro Minato,Makoto Mark Taketo +12 more
TL;DR: It is shown that a new type of immature myeloid cell (iMC) is recruited from the bone marrow to the tumor invasion front and accumulation of iMCs that promote tumor invasion in cis-Apc/Smad4 mice.
Journal ArticleDOI
Pivotal role of CXCR3 in melanoma cell metastasis to lymph nodes.
Kenji Kawada,Masahiro Sonoshita,Hiromi Sakashita,Arimichi Takabayashi,Yoshio Yamaoka,Toshiaki Manabe,Kayo Inaba,Nagahiro Minato,Masanobu Oshima,Makoto Mark Taketo +9 more
TL;DR: It is shown that mouse B16F10 melanoma cells constitutively express chemokine receptor CXCR3, and that its ligands CXCL9/Mig, CxCL10/IP-10, and CX CL11/I-TAC induce cellular responses in vitro, such as actin polymerization, migration, invasion, and cell survival.
Journal ArticleDOI
Involvement of vascular endothelial growth factor receptor-3 in maintenance of integrity of endothelial cell lining during tumor angiogenesis.
Hajime Kubo,Takashi Fujiwara,Takashi Fujiwara,Takashi Fujiwara,Lotta Jussila,Lotta Jussila,Lotta Jussila,Hiroyuki Hashi,Hiroyuki Hashi,Hiroyuki Hashi,Minetaro Ogawa,Minetaro Ogawa,Minetaro Ogawa,Kenji Shimizu,Kenji Shimizu,Kenji Shimizu,Masaaki Awane,Masaaki Awane,Masaaki Awane,Yoshiharu Sakai,Yoshiharu Sakai,Yoshiharu Sakai,Arimichi Takabayashi,Arimichi Takabayashi,Arimichi Takabayashi,Kari Alitalo,Kari Alitalo,Kari Alitalo,Yoshio Yamaoka,Yoshio Yamaoka,Yoshio Yamaoka,Shin-Ichi Nishikawa,Shin-Ichi Nishikawa,Shin-Ichi Nishikawa +33 more
TL;DR: It is demonstrated that the inactivation of VEGFR-3 by a novel blocking monoclonal antibody (mAb) suppresses tumor growth by inhibiting the neo-angiogenesis of tumor-bearing tissues and suggests that the VEGF-C/VEG FR-3 pathway may serve another candidate target for cancer therapy.